Josien H - Search Results

1

Topographic analysis of the S7 binding subsite of the tachykinin neurokinin-1 receptor.

Josien H, Convert O, Berlose JP, Sagan S, Brunissen A, Lavielle S, Chassaing G. Josien H, et al. Biopolymers. 1996 Aug;39(2):133-47. doi: 10.1002/(SICI)1097-0282(199608)39:2%3C133::AID-BIP2%3E3.0.CO;2-Q. Biopolymers. 1996. PMID: 8679946

2

Design and synthesis of side-chain conformationally restricted phenylalanines and their use for structure-activity studies on tachykinin NK-1 receptor.

Josien H, Lavielle S, Brunissen A, Saffroy M, Torrens Y, Beaujouan JC, Glowinski J, Chassaing G. Josien H, et al. J Med Chem. 1994 May 27;37(11):1586-601. doi: 10.1021/jm00037a009. J Med Chem. 1994. PMID: 7515443

3

Use of conformationally constrained peptides for a topographical analysis of the combing site of a monoclonal anti-substance P antibody.

Déry O, Josien H, Grassi J, Chassaing G, Couraud JY, Lavielle S. Déry O, et al. Among authors: josien h. Biopolymers. 1996 Jul;39(1):67-74. doi: 10.1002/(sici)1097-0282(199607)39:1<67::aid-bip7>3.0.co;2-t. Biopolymers. 1996. PMID: 8924627

4

Tachykinin NK-1 receptor probed with constrained analogues of substance P.

Sagan S, Josien H, Karoyan P, Brunissen A, Chassaing G, Lavielle S. Sagan S, et al. Among authors: josien h. Bioorg Med Chem. 1996 Dec;4(12):2167-78. doi: 10.1016/s0968-0896(96)00230-1. Bioorg Med Chem. 1996. PMID: 9022979

5

Design, synthesis and biological evaluation of indane derived GPR40 agoPAMs.

Pio B, Chobanian HR, Guo Y, Josien H, Hagmann WK, Miller M, Trujillo ME, Kirkland M, Kosinski D, Mane J, Pachanski M, Cheewatrakoolpong B, Ashley E, Orr R, Wright MJ, Bugianesi R, Souza S, Zhang X, Di Salvo J, Weinglass AB, Tschirret-Guth R, Samuel K, Chen Q, Shang J, Lamca J, Ehrhart J, Nargund R, Howard AD, Colletti SL. Pio B, et al. Among authors: josien h. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1842-1848. doi: 10.1016/j.bmcl.2019.04.050. Epub 2019 May 2. Bioorg Med Chem Lett. 2019. PMID: 31109791

6

Metabolic stabilization of benzylidene ketal M(2) muscarinic receptor antagonists via halonaphthoic acid substitution.

Boyle CD, Chackalamannil S, Clader JW, Greenlee WJ, Josien HB, Kaminski JJ, Kozlowski JA, McCombie SW, Nazareno DV, Tagat JR, Wang Y, Zhou G, Billard W, Binch H, Crosby G, Cohen-Williams M, Coffin VL, Cox KA, Grotz DE, Duffy RA, Ruperto V, Lachowicz JE. Boyle CD, et al. Among authors: josien hb. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2311-4. doi: 10.1016/s0960-894x(01)00435-8. Bioorg Med Chem Lett. 2001. PMID: 11527721

7

Synthesis, SAR, and biological evaluation of oximino-piperidino-piperidine amides. 1. Orally bioavailable CCR5 receptor antagonists with potent anti-HIV activity.

Palani A, Shapiro S, Josien H, Bara T, Clader JW, Greenlee WJ, Cox K, Strizki JM, Baroudy BM. Palani A, et al. Among authors: josien h. J Med Chem. 2002 Jul 4;45(14):3143-60. doi: 10.1021/jm0200815. J Med Chem. 2002. PMID: 12086500

8

Tetrahydroquinoline sulfonamides as gamma-secretase inhibitors.

Asberom T, Bara TA, Clader JW, Greenlee WJ, Guzik HS, Josien HB, Li W, Parker EM, Pissarnitski DA, Song L, Zhang L, Zhao Z. Asberom T, et al. Bioorg Med Chem Lett. 2007 Jan 1;17(1):205-7. doi: 10.1016/j.bmcl.2006.09.064. Epub 2006 Oct 12. Bioorg Med Chem Lett. 2007. PMID: 17046254

9

Discovery of 2,4,6-trisubstituted N-arylsulfonyl piperidines as gamma-secretase inhibitors.

Li H, Asberom T, Bara TA, Clader JW, Greenlee WJ, Josien HB, McBriar MD, Nomeir A, Pissarnitski DA, Rajagopalan M, Xu R, Zhao Z, Song L, Zhang L. Li H, et al. Among authors: josien hb. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6290-4. doi: 10.1016/j.bmcl.2007.09.006. Epub 2007 Sep 7. Bioorg Med Chem Lett. 2007. PMID: 17890085

10

Cyclic hydroxyamidines as amide isosteres: discovery of oxadiazolines and oxadiazines as potent and highly efficacious γ-secretase modulators in vivo.

Sun ZY, Asberom T, Bara T, Bennett C, Burnett D, Chu I, Clader J, Cohen-Williams M, Cole D, Czarniecki M, Durkin J, Gallo G, Greenlee W, Josien H, Huang X, Hyde L, Jones N, Kazakevich I, Li H, Liu X, Lee J, Maccoss M, Mandal MB, McCracken T, Nomeir A, Mazzola R, Palani A, Parker EM, Pissarnitski DA, Qin J, Song L, Terracina G, Vicarel M, Voigt J, Xu R, Zhang L, Zhang Q, Zhao Z, Zhu X, Zhu Z. Sun ZY, et al. Among authors: josien h. J Med Chem. 2012 Jan 12;55(1):489-502. doi: 10.1021/jm201407j. Epub 2011 Dec 8. J Med Chem. 2012. PMID: 22098494

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

36 results

Search Page

Filters