Shimada T - Search Results

1

Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomes.

Yamazaki H, Nakano M, Gillam EM, Bell LC, Guengerich FP, Shimada T. Yamazaki H, et al. Among authors: shimada t. Biochem Pharmacol. 1996 Jul 26;52(2):301-9. doi: 10.1016/0006-2952(96)00208-0. Biochem Pharmacol. 1996. PMID: 8694855

2

Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes.

Yamazaki H, Inoue K, Hashimoto M, Shimada T. Yamazaki H, et al. Among authors: shimada t. Arch Toxicol. 1999 Mar;73(2):65-70. doi: 10.1007/s002040050588. Arch Toxicol. 1999. PMID: 10350185

3

Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase.

Shimada T, Gillam EM, Oda Y, Tsumura F, Sutter TR, Guengerich FP, Inoue K. Shimada T, et al. Chem Res Toxicol. 1999 Jul;12(7):623-9. doi: 10.1021/tx990028s. Chem Res Toxicol. 1999. PMID: 10409402

4

Prediction of human liver microsomal oxidations of 7-ethoxycoumarin and chlorzoxazone with kinetic parameters of recombinant cytochrome P-450 enzymes.

Shimada T, Tsumura F, Yamazaki H. Shimada T, et al. Drug Metab Dispos. 1999 Nov;27(11):1274-80. Drug Metab Dispos. 1999. PMID: 10534312

5

Roles of NADPH-P450 reductase in the O-deethylation of 7-ethoxycoumarin by recombinant human cytochrome P450 1B1 variants in Escherichia coli.

Shimada T, Tsumura F, Gillam EM, Guengerich FP, Inoue K. Shimada T, et al. Protein Expr Purif. 2000 Oct;20(1):73-80. doi: 10.1006/prep.2000.1302. Protein Expr Purif. 2000. PMID: 11035953

6

Characterization of liver microsomal 7-ethoxycoumarin O-deethylation and chlorzoxazone 6-hydroxylation activities in Japanese and Caucasian subjects genotyped for CYP2E1 gene.

Inoue K, Yamazaki H, Shimada T. Inoue K, et al. Among authors: shimada t. Arch Toxicol. 2000 Sep;74(7):372-8. doi: 10.1007/s002040000151. Arch Toxicol. 2000. PMID: 11043492

7

Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.

Oda Y, Aryal P, Terashita T, Gillam EM, Guengerich FP, Shimada T. Oda Y, et al. Among authors: shimada t. Mutat Res. 2001 May 31;492(1-2):81-90. doi: 10.1016/s1383-5718(01)00154-1. Mutat Res. 2001. PMID: 11377247

8

Stimulation of cytochrome P450 reactions by apo-cytochrome b5: evidence against transfer of heme from cytochrome P450 3A4 to apo-cytochrome b5 or heme oxygenase.

Yamazaki H, Shimada T, Martin MV, Guengerich FP. Yamazaki H, et al. Among authors: shimada t. J Biol Chem. 2001 Aug 17;276(33):30885-91. doi: 10.1074/jbc.M105011200. Epub 2001 Jun 18. J Biol Chem. 2001. PMID: 11413149 Free article.

9

Specificity of 17beta-oestradiol and benzo[a]pyrene oxidation by polymorphic human cytochrome P4501B1 variants substituted at residues 48, 119 and 432.

Shimada T, Watanabe J, Inoue K, Guengerich FP, Gillam EM. Shimada T, et al. Xenobiotica. 2001 Mar;31(3):163-76. doi: 10.1080/00498250110043490. Xenobiotica. 2001. PMID: 11465393

10

Cytochrome P450 reconstitution systems.

Shimada T, Yamazaki H. Shimada T, et al. Methods Mol Biol. 1998;107:85-93. doi: 10.1385/0-89603-519-0:85. Methods Mol Biol. 1998. PMID: 14577215 No abstract available.

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