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Modulation of very low density lipoprotein production and clearance contributes to age- and gender- dependent hyperlipoproteinemia in apolipoprotein E3-Leiden transgenic mice.
van Vlijmen BJ, van 't Hof HB, Mol MJ, van der Boom H, van der Zee A, Frants RR, Hofker MH, Havekes LM. van Vlijmen BJ, et al. Among authors: van der boom h, van t hof hb, van der zee a. J Clin Invest. 1996 Mar 1;97(5):1184-92. doi: 10.1172/JCI118532. J Clin Invest. 1996. PMID: 8636429 Free PMC article.
In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2(Arg-158 --> Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice.
van Vlijmen BJ, van Dijk KW, van't Hof HB, van Gorp PJ, van der Zee A, van der Boom H, Breuer ML, Hofker MH, Havekes LM. van Vlijmen BJ, et al. Among authors: van gorp pj, van dijk kw, van der boom h, van t hof hb, van der zee a. J Biol Chem. 1996 Nov 29;271(48):30595-602. doi: 10.1074/jbc.271.48.30595. J Biol Chem. 1996. PMID: 8940032 Free article.
Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-Leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor.
van Dijk KW, van Vlijmen BJ, van der Zee A, van't Hof B, van der Boom H, Kobayashi K, Chan L, Havekes LM, Hofker MH. van Dijk KW, et al. Among authors: van vlijmen bj, van der boom h, van der zee a, van t hof b. Arterioscler Thromb Vasc Biol. 1998 Jan;18(1):7-12. doi: 10.1161/01.atv.18.1.7. Arterioscler Thromb Vasc Biol. 1998. PMID: 9445249
Hyperlipidemia of ApoE2(Arg(158)-Cys) and ApoE3-Leiden transgenic mice is modulated predominantly by LDL receptor expression.
van Dijk KW, van Vlijmen BJ, de Winther MP, van 't Hof B, van der Zee A, van der Boom H, Havekes LM, Hofker MH. van Dijk KW, et al. Among authors: van vlijmen bj, van der boom h, van der zee a, van t hof b. Arterioscler Thromb Vasc Biol. 1999 Dec;19(12):2945-51. doi: 10.1161/01.atv.19.12.2945. Arterioscler Thromb Vasc Biol. 1999. PMID: 10591674
Apolipoprotein E2 (Lys146-->Gln) causes hypertriglyceridemia due to an apolipoprotein E variant-specific inhibition of lipolysis of very low density lipoproteins-triglycerides.
de Beer F, van Dijk KW, Jong MC, van Vark LC, van der Zee A, Hofker MH, Fallaux FJ, Hoeben RC, Smelt AH, Havekes LM. de Beer F, et al. Among authors: van dijk kw, van vark lc, van der zee a. Arterioscler Thromb Vasc Biol. 2000 Jul;20(7):1800-6. doi: 10.1161/01.atv.20.7.1800. Arterioscler Thromb Vasc Biol. 2000. PMID: 10894820
In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE.
van Dijk KW, van Vlijmen BJ, van't Hof HB, van der Zee A, Santamarina-Fojo S, van Berkel TJ, Havekes LM, Hofker MH. van Dijk KW, et al. Among authors: van vlijmen bj, van berkel tj, van t hof hb, van der zee a. J Lipid Res. 1999 Feb;40(2):336-44. J Lipid Res. 1999. PMID: 9925664 Free article.
-van Dijk, K. W., B. J. M. Van Vlijmen, H. B. van't Hof, A. van der Zee, S. Santamarina-Fojo, T. J. C. van Berkel, L. M. Havekes, and M. H. Hofker. In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires …
-van Dijk, K. W., B. J. M. Van Vlijmen, H. B. van't Hof, A. van der Zee, S. Santamarina-Foj …
395 results