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Antagonist pharmacology of metabotropic glutamate receptors coupled to phospholipase D activation in adult rat hippocampus: focus on (2R,1'S,2'R,3'S)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine versus 3, 5-dihydroxyphenylglycine.
Albani-Torregrossa S, Attucci S, Marinozzi M, Pellicciari R, Moroni F, Pellegrini-Giampietro DE. Albani-Torregrossa S, et al. Among authors: marinozzi m. Mol Pharmacol. 1999 Apr;55(4):699-707. Mol Pharmacol. 1999. PMID: 10101028
Synthesis and pharmacological characterization of all sixteen stereoisomers of 2-(2'-carboxy-3'-phenylcyclopropyl)glycine. Focus on (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a novel and selective group II metabotropic glutamate receptors antagonist.
Pellicciari R, Marinozzi M, Natalini B, Costantino G, Luneia R, Giorgi G, Moroni F, Thomsen C. Pellicciari R, et al. Among authors: marinozzi m. J Med Chem. 1996 May 24;39(11):2259-69. doi: 10.1021/jm960059+. J Med Chem. 1996. PMID: 8667369
Type 2 metabotropic glutamate (mGlu) receptors tonically inhibit transmitter release in rat caudate nucleus: in vivo studies with (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a new potent and selective antagonist.
Cozzi A, Attucci S, Peruginelli F, Marinozzi M, Luneia R, Pellicciari R, Moroni F. Cozzi A, et al. Among authors: marinozzi m. Eur J Neurosci. 1997 Jul;9(7):1350-5. doi: 10.1111/j.1460-9568.1997.tb01489.x. Eur J Neurosci. 1997. PMID: 9240392
(2R,1'S,2'R,3'S)-2-(2'-Carboxy-3'-phenylcyclopropyl)glycine (PCCG-13), the first potent and selective competitive antagonist of phospholipase D-coupled metabotropic glutamate receptors: asymmetric synthesis and preliminary biological properties.
Pellicciari R, Marinozzi M, Costantino G, Natalini B, Moroni F, Pellegrini-Giampietro D. Pellicciari R, et al. Among authors: marinozzi m. J Med Chem. 1999 Jul 15;42(14):2716-20. doi: 10.1021/jm990128v. J Med Chem. 1999. PMID: 10411492
102 results