O'Connor M - Search Results

1

DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite.

Szabó C, Zingarelli B, O'Connor M, Salzman AL. Szabó C, et al. Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):1753-8. doi: 10.1073/pnas.93.5.1753. Proc Natl Acad Sci U S A. 1996. PMID: 8700830 Free PMC article.

2

Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide.

Zingarelli B, O'Connor M, Wong H, Salzman AL, Szabó C. Zingarelli B, et al. J Immunol. 1996 Jan 1;156(1):350-8. J Immunol. 1996. PMID: 8598485

3

Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform.

Southan GJ, Zingarelli B, O'Connor M, Salzman AL, Szabó C. Southan GJ, et al. Br J Pharmacol. 1996 Feb;117(4):619-32. doi: 10.1111/j.1476-5381.1996.tb15236.x. Br J Pharmacol. 1996. PMID: 8646406 Free PMC article.

4

Induction and activity of nitric oxide synthase in cultured human intestinal epithelial monolayers.

Salzman A, Denenberg AG, Ueta I, O'Connor M, Linn SC, Szabó C. Salzman A, et al. Am J Physiol. 1996 Apr;270(4 Pt 1):G565-73. doi: 10.1152/ajpgi.1996.270.4.G565. Am J Physiol. 1996. PMID: 8928785

5

The inhibitory effects of mercaptoalkylguanidines on cyclo-oxygenase activity.

Zingarelli B, Southan GJ, Gilad E, O'Connor M, Salzman AL, Szabó C. Zingarelli B, et al. Br J Pharmacol. 1997 Feb;120(3):357-66. doi: 10.1038/sj.bjp.0700892. Br J Pharmacol. 1997. PMID: 9031736 Free PMC article.

6

Peroxynitrite causes energy depletion and increases permeability via activation of poly (ADP-ribose) synthetase in pulmonary epithelial cells.

Szabó C, Saunders C, O'Connor M, Salzman AL. Szabó C, et al. Am J Respir Cell Mol Biol. 1997 Feb;16(2):105-9. doi: 10.1165/ajrcmb.16.2.9032115. Am J Respir Cell Mol Biol. 1997. PMID: 9032115

7

Endogenously produced peroxynitrite induces the oxidation of mitochondrial and nuclear proteins in immunostimulated macrophages.

Szabó C, O'Connor M, Salzman AL. Szabó C, et al. FEBS Lett. 1997 Jun 9;409(2):147-50. doi: 10.1016/s0014-5793(97)00466-3. FEBS Lett. 1997. PMID: 9202135 Free article.

8

Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite.

Szabó C, Cuzzocrea S, Zingarelli B, O'Connor M, Salzman AL. Szabó C, et al. J Clin Invest. 1997 Aug 1;100(3):723-35. doi: 10.1172/JCI119585. J Clin Invest. 1997. PMID: 9239421 Free PMC article.

9

Ursodeoxycholate inhibits induction of NOS in human intestinal epithelial cells and in vivo.

Invernizzi P, Salzman AL, Szabó C, Ueta I, O'Connor M, Setchell KD. Invernizzi P, et al. Am J Physiol. 1997 Jul;273(1 Pt 1):G131-8. doi: 10.1152/ajpgi.1997.273.1.G131. Am J Physiol. 1997. PMID: 9252519

10

Role of peroxynitrite and activation of poly (ADP-ribose) synthase in the vascular failure induced by zymosan-activated plasma.

Cuzzocrea S, Zingarelli B, O'Connor M, Salzman AL, Caputi AP, Szabó C. Cuzzocrea S, et al. Br J Pharmacol. 1997 Oct;122(3):493-503. doi: 10.1038/sj.bjp.0701387. Br J Pharmacol. 1997. PMID: 9351506 Free PMC article.

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