Blättler WA - Search Results

1

Eradication of large colon tumor xenografts by targeted delivery of maytansinoids.

Liu C, Tadayoni BM, Bourret LA, Mattocks KM, Derr SM, Widdison WC, Kedersha NL, Ariniello PD, Goldmacher VS, Lambert JM, Blättler WA, Chari RV. Liu C, et al. Among authors: blattler wa. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8618-23. doi: 10.1073/pnas.93.16.8618. Proc Natl Acad Sci U S A. 1996. PMID: 8710920 Free PMC article.

2

Immunoconjugates containing novel maytansinoids: promising anticancer drugs.

Chari RV, Martell BA, Gross JL, Cook SB, Shah SA, Blättler WA, McKenzie SJ, Goldmacher VS. Chari RV, et al. Among authors: blattler wa. Cancer Res. 1992 Jan 1;52(1):127-31. Cancer Res. 1992. PMID: 1727373

3

Enhancement of the selectivity and antitumor efficacy of a CC-1065 analogue through immunoconjugate formation.

Chari RV, Jackel KA, Bourret LA, Derr SM, Tadayoni BM, Mattocks KM, Shah SA, Liu C, Blättler WA, Goldmacher VS. Chari RV, et al. Among authors: blattler wa. Cancer Res. 1995 Sep 15;55(18):4079-84. Cancer Res. 1995. PMID: 7545085

4

Cure of multidrug-resistant human B-cell lymphoma xenografts by combinations of anti-B4-blocked ricin and chemotherapeutic drugs.

Liu C, Lambert JM, Teicher BA, Blättler WA, O'Connor R. Liu C, et al. Among authors: blattler wa. Blood. 1996 May 1;87(9):3892-8. Blood. 1996. PMID: 8611717 Free article.

5

Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing.

Erickson HK, Park PU, Widdison WC, Kovtun YV, Garrett LM, Hoffman K, Lutz RJ, Goldmacher VS, Blättler WA. Erickson HK, et al. Among authors: blattler wa. Cancer Res. 2006 Apr 15;66(8):4426-33. doi: 10.1158/0008-5472.CAN-05-4489. Cancer Res. 2006. PMID: 16618769

6

Semisynthetic maytansine analogues for the targeted treatment of cancer.

Widdison WC, Wilhelm SD, Cavanagh EE, Whiteman KR, Leece BA, Kovtun Y, Goldmacher VS, Xie H, Steeves RM, Lutz RJ, Zhao R, Wang L, Blättler WA, Chari RV. Widdison WC, et al. Among authors: blattler wa. J Med Chem. 2006 Jul 13;49(14):4392-408. doi: 10.1021/jm060319f. J Med Chem. 2006. PMID: 16821799

7

Structural characterization of the maytansinoid-monoclonal antibody immunoconjugate, huN901-DM1, by mass spectrometry.

Wang L, Amphlett G, Blättler WA, Lambert JM, Zhang W. Wang L, et al. Among authors: blattler wa. Protein Sci. 2005 Sep;14(9):2436-46. doi: 10.1110/ps.051478705. Epub 2005 Aug 4. Protein Sci. 2005. PMID: 16081651 Free PMC article.

8

Correlation between in vivo toxicity and preclinical in vitro parameters for the immunotoxin anti-B4-blocked ricin.

Grossbard ML, Lambert JM, Goldmacher VS, Blättler WA, Nadler LM. Grossbard ML, et al. Among authors: blattler wa. Cancer Res. 1992 Aug 1;52(15):4200-7. Cancer Res. 1992. PMID: 1379121 Clinical Trial.

9

Photoactivation of toxin conjugates.

Goldmacher VS, Senter PD, Lambert JM, Blättler WA. Goldmacher VS, et al. Among authors: blattler wa. Bioconjug Chem. 1992 Mar-Apr;3(2):104-7. doi: 10.1021/bc00014a003. Bioconjug Chem. 1992. PMID: 1515463

10

The specific cytotoxicity of immunoconjugates containing blocked ricin is dependent on the residual binding capacity of blocked ricin: evidence that the membrane binding and A-chain translocation activities of ricin cannot be separated.

Goldmacher VS, Lambert JM, Blättler WA. Goldmacher VS, et al. Among authors: blattler wa. Biochem Biophys Res Commun. 1992 Mar 16;183(2):758-66. doi: 10.1016/0006-291x(92)90548-y. Biochem Biophys Res Commun. 1992. PMID: 1550582

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