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Crystal structures of complexes of a peptidic inhibitor with wild-type and two mutant HIV-1 proteases.
Hong L, Treharne A, Hartsuck JA, Foundling S, Tang J. Hong L, et al. Among authors: foundling s. Biochemistry. 1996 Aug 20;35(33):10627-33. doi: 10.1021/bi960481s. Biochemistry. 1996. PMID: 8718851
Comparison of the three crystal structures provides explanations which are consistent with the known kinetic properties of these mutant enzymes with the U-89360E inhibitor [Lin, Y., Lin, X., Hong, L., Foundling, S., Heinrikson, R. L., Thaisrivongs, S., Leelam …
Comparison of the three crystal structures provides explanations which are consistent with the known kinetic properties of these mutant enzy …
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