Chatelain R - Search Results

1

Mercaptoacyl dipeptides as orally active dual inhibitors of angiotensin-converting enzyme and neutral endopeptidase.

Fink CA, Carlson JE, McTaggart PA, Qiao Y, Webb R, Chatelain R, Jeng AY, Trapani AJ. Fink CA, et al. Among authors: chatelain r. J Med Chem. 1996 Aug 2;39(16):3158-68. doi: 10.1021/jm960323z. J Med Chem. 1996. PMID: 8759637

2

Antihypertensive and natriuretic effects of CGS 30440, a dual inhibitor of angiotensin-converting enzyme and neutral endopeptidase 24.11.

Chatelain RE, Ghai RD, Trapani AJ, Odorico LM, Dardik BN, De Lombaert S, Lappe RW, Fink CA. Chatelain RE, et al. J Pharmacol Exp Ther. 1998 Mar;284(3):974-82. J Pharmacol Exp Ther. 1998. PMID: 9495857

3

Effects of the novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme, CGS 30440, on blood pressure and cardiac hypertrophy in spontaneously hypertensive rats.

Webb RL, Abramson ML, Beil ME, Odorico LM, Chatelain RE. Webb RL, et al. Among authors: chatelain re. J Cardiovasc Pharmacol. 1997 Nov;30(5):632-42. doi: 10.1097/00005344-199711000-00014. J Cardiovasc Pharmacol. 1997. PMID: 9388046

4

Perhydroquinolylbenzamides as novel inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.

Coppola GM, Kukkola PJ, Stanton JL, Neubert AD, Marcopulos N, Bilci NA, Wang H, Tomaselli HC, Tan J, Aicher TD, Knorr DC, Jeng AY, Dardik B, Chatelain RE. Coppola GM, et al. J Med Chem. 2005 Oct 20;48(21):6696-712. doi: 10.1021/jm058228q. J Med Chem. 2005. PMID: 16220986

5

Glucocorticoid receptor antagonism by cyproterone acetate and RU486.

Honer C, Nam K, Fink C, Marshall P, Ksander G, Chatelain RE, Cornell W, Steele R, Schweitzer R, Schumacher C. Honer C, et al. Among authors: chatelain re. Mol Pharmacol. 2003 May;63(5):1012-20. doi: 10.1124/mol.63.5.1012. Mol Pharmacol. 2003. PMID: 12695529

6

Antihypertensive effects of CGS 19281A, an inhibitor of phenylethanolamine-N-methyltransferase.

Chatelain RE, Manniello MJ, Dardik BN, Rizzo M, Brosnihan KB. Chatelain RE, et al. J Pharmacol Exp Ther. 1990 Jan;252(1):117-25. J Pharmacol Exp Ther. 1990. PMID: 2153796

7

A quantitative assay for the non-covalent association between apolipoprotein[a] and apolipoprotein B: an alternative measure of Lp[a] assembly.

Dardik BN, Schwartzkopf CD, Stevens DE, Chatelain RE. Dardik BN, et al. Among authors: chatelain re. J Lipid Res. 2000 Jun;41(6):1013-9. J Lipid Res. 2000. PMID: 10828094 Free article.

8

Elevated arterial cyclic AMP levels during the development of one-kidney, one-clip and DOCA hypertension in rats.

Dardik BN, DiBello PM, Chatelain RE. Dardik BN, et al. Among authors: chatelain re. Eur J Pharmacol. 1988 Dec 6;158(1-2):139-43. doi: 10.1016/0014-2999(88)90263-4. Eur J Pharmacol. 1988. PMID: 2851454

9

Increased DNA replication in the arterial adventitia after aortic ligation.

Chatelain RE, Dardik BN. Chatelain RE, et al. Hypertension. 1988 Feb;11(2 Pt 2):I130-4. doi: 10.1161/01.hyp.11.2_pt_2.i130. Hypertension. 1988. PMID: 3346048

10

Discovery of an Orally Bioavailable Benzimidazole Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor That Suppresses Body Weight Gain in Diet-Induced Obese Dogs and Postprandial Triglycerides in Humans.

Nakajima K, Chatelain R, Clairmont KB, Commerford R, Coppola GM, Daniels T, Forster CJ, Gilmore TA, Gong Y, Jain M, Kanter A, Kwak Y, Li J, Meyers CD, Neubert AD, Szklennik P, Tedesco V, Thompson J, Truong D, Yang Q, Hubbard BK, Serrano-Wu MH. Nakajima K, et al. Among authors: chatelain r. J Med Chem. 2017 Jun 8;60(11):4657-4664. doi: 10.1021/acs.jmedchem.7b00173. Epub 2017 May 24. J Med Chem. 2017. PMID: 28498655 Clinical Trial.

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