Fredericks ZL - Search Results

1

Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location, structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies.

Pitcher JA, Fredericks ZL, Stone WC, Premont RT, Stoffel RH, Koch WJ, Lefkowitz RJ. Pitcher JA, et al. Among authors: fredericks zl. J Biol Chem. 1996 Oct 4;271(40):24907-13. doi: 10.1074/jbc.271.40.24907. J Biol Chem. 1996. PMID: 8798768 Free article.

2

Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta2-adrenergic receptor.

Fredericks ZL, Pitcher JA, Lefkowitz RJ. Fredericks ZL, et al. J Biol Chem. 1996 Jun 7;271(23):13796-803. doi: 10.1074/jbc.271.23.13796. J Biol Chem. 1996. PMID: 8662852 Free article.

3

Clathrin-mediated endocytosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of beta-arrestin1.

Lin FT, Krueger KM, Kendall HE, Daaka Y, Fredericks ZL, Pitcher JA, Lefkowitz RJ. Lin FT, et al. Among authors: fredericks zl. J Biol Chem. 1997 Dec 5;272(49):31051-7. doi: 10.1074/jbc.272.49.31051. J Biol Chem. 1997. PMID: 9388255 Free article.

4

Minimal determinants for binding activated G alpha from the structure of a G alpha(i1)-peptide dimer.

Johnston CA, Lobanova ES, Shavkunov AS, Low J, Ramer JK, Blaesius R, Fredericks Z, Willard FS, Kuhlman B, Arshavsky VY, Siderovski DP. Johnston CA, et al. Biochemistry. 2006 Sep 26;45(38):11390-400. doi: 10.1021/bi0613832. Biochemistry. 2006. PMID: 16981699 Free PMC article.

5

A bifunctional Galphai/Galphas modulatory peptide that attenuates adenylyl cyclase activity.

Johnston CA, Ramer JK, Blaesius R, Fredericks Z, Watts VJ, Siderovski DP. Johnston CA, et al. FEBS Lett. 2005 Oct 24;579(25):5746-50. doi: 10.1016/j.febslet.2005.09.059. FEBS Lett. 2005. PMID: 16225870 Free PMC article.

6

Detection of small-molecule enzyme inhibitors with peptides isolated from phage-displayed combinatorial peptide libraries.

Hyde-DeRuyscher R, Paige LA, Christensen DJ, Hyde-DeRuyscher N, Lim A, Fredericks ZL, Kranz J, Gallant P, Zhang J, Rocklage SM, Fowlkes DM, Wendler PA, Hamilton PT. Hyde-DeRuyscher R, et al. Among authors: fredericks zl. Chem Biol. 2000 Jan;7(1):17-25. doi: 10.1016/s1074-5521(00)00062-4. Chem Biol. 2000. PMID: 10662687

7

Exploring the interface between the N- and C-terminal helices of cytochrome c by random mutagenesis within the C-terminal helix.

Fredericks ZL, Pielak GJ. Fredericks ZL, et al. Biochemistry. 1993 Jan 26;32(3):929-36. doi: 10.1021/bi00054a026. Biochemistry. 1993. PMID: 8380714

8

Structure of Galpha(i1) bound to a GDP-selective peptide provides insight into guanine nucleotide exchange.

Johnston CA, Willard FS, Jezyk MR, Fredericks Z, Bodor ET, Jones MB, Blaesius R, Watts VJ, Harden TK, Sondek J, Ramer JK, Siderovski DP. Johnston CA, et al. Structure. 2005 Jul;13(7):1069-80. doi: 10.1016/j.str.2005.04.007. Structure. 2005. PMID: 16004878 Free PMC article.

9

Protein thermal denaturation, side-chain models, and evolution: amino acid substitutions at a conserved helix-helix interface.

Pielak GJ, Auld DS, Beasley JR, Betz SF, Cohen DS, Doyle DF, Finger SA, Fredericks ZL, Hilgen-Willis S, Saunders AJ, et al. Pielak GJ, et al. Among authors: fredericks zl. Biochemistry. 1995 Mar 14;34(10):3268-76. doi: 10.1021/bi00010a017. Biochemistry. 1995. PMID: 7880822

10

Identification and characterization of peptide probes directed against PKCalpha conformations.

Ashraf SS, Anderson E, Duke K, Hamilton PT, Fredericks Z. Ashraf SS, et al. J Pept Res. 2003 May;61(5):263-73. doi: 10.1034/j.1399-3011.2003.00056.x. J Pept Res. 2003. PMID: 12662360

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