Obara T - Search Results

1

New neplanocin analogues. 7. Synthesis and antiviral activity of 2-halo derivatives of neplanocin A.

Obara T, Shuto S, Saito Y, Snoeck R, Andrei G, Balzarini J, De Clercq E, Matsuda A. Obara T, et al. J Med Chem. 1996 Sep 13;39(19):3847-52. doi: 10.1021/jm960145+. J Med Chem. 1996. PMID: 8809173

2

New neplanocin analogues. 6. Synthesis and potent antiviral activity of 6'-homoneplanocin A1.

Shuto S, Obara T, Saito Y, Andrei G, Snoeck R, De Clercq E, Matsuda A. Shuto S, et al. Among authors: obara t. J Med Chem. 1996 Jun 7;39(12):2392-9. doi: 10.1021/jm950853f. J Med Chem. 1996. PMID: 8691433

3

New neplanocin analogues. IX. A practical preparation of (6'R)-6'-C-methylneplanocin A (RMNPA), a potent antiviral agent, and the determination of its 6'-configuration. Diastereoselective deamination by adenosine deaminase.

Shuto S, Obara T, Yaginuma S, Matsuda A. Shuto S, et al. Among authors: obara t. Chem Pharm Bull (Tokyo). 1997 Jan;45(1):138-42. doi: 10.1248/cpb.45.138. Chem Pharm Bull (Tokyo). 1997. PMID: 9023976

4

New neplanocin analogues. VIII. Synthesis and biological activity of 6'-C-ethyl, -ethenyl, and -ethynyl derivatives of neplanocin A.

Shuto S, Obara T, Saito Y, Yamashita K, Tanaka M, Sasaki T, Andrei G, Snoeck R, Neyts J, Padalko E, Balzarini J, De Clercq E, Matsuda A. Shuto S, et al. Among authors: obara t. Chem Pharm Bull (Tokyo). 1997 Jul;45(7):1163-8. doi: 10.1248/cpb.45.1163. Chem Pharm Bull (Tokyo). 1997. PMID: 9246750

5

New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents.

Shuto S, Obara T, Toriya M, Hosoya M, Snoeck R, Andrei G, Balzarini J, De Clercq E. Shuto S, et al. Among authors: obara t. J Med Chem. 1992 Jan 24;35(2):324-31. doi: 10.1021/jm00080a018. J Med Chem. 1992. PMID: 1732550

6

New neplanocin analogues. Synthesis and antiviral activity of 6'-modified neplanocin A derivatives.

Shuto S, Obara T, De Clercq E. Shuto S, et al. Among authors: obara t. Nucleic Acids Symp Ser. 1991;(25):7-8. Nucleic Acids Symp Ser. 1991. PMID: 1842101

7

New neplanocin analogues. IV. 2-Fluoroneplanocin A: an adenosine deaminase-resistant equivalent of neplanocin A.

Shuto S, Obara T, Itoh H, Kosugi Y, Saito Y, Toriya M, Yaginuma S, Shigeta S, Matsuda A. Shuto S, et al. Among authors: obara t. Chem Pharm Bull (Tokyo). 1994 Aug;42(8):1688-90. doi: 10.1248/cpb.42.1688. Chem Pharm Bull (Tokyo). 1994. PMID: 7954923

8

Antiviral activities of ribavirin, 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide, and 6'-(R)-6'-C-methylneplanocin A against several ortho- and paramyxoviruses.

Shigeta S, Mori S, Baba M, Ito M, Honzumi K, Nakamura K, Oshitani H, Numazaki Y, Matsuda A, Obara T, et al. Shigeta S, et al. Among authors: obara t. Antimicrob Agents Chemother. 1992 Feb;36(2):435-9. doi: 10.1128/AAC.36.2.435. Antimicrob Agents Chemother. 1992. PMID: 1605607 Free PMC article.

9

Isolation of a second yeast Saccharomyces cerevisiae gene (GPA2) coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions.

Nakafuku M, Obara T, Kaibuchi K, Miyajima I, Miyajima A, Itoh H, Nakamura S, Arai K, Matsumoto K, Kaziro Y. Nakafuku M, et al. Among authors: obara t. Proc Natl Acad Sci U S A. 1988 Mar;85(5):1374-8. doi: 10.1073/pnas.85.5.1374. Proc Natl Acad Sci U S A. 1988. PMID: 2830616 Free PMC article.

10

Structures of the genes coding for G-protein alpha subunits from mammalian and yeast cells.

Kaziro Y, Itoh H, Kozasa T, Toyama R, Tsukamoto T, Matsuoka M, Nakafuku M, Obara T, Takagi T, Hernandez R. Kaziro Y, et al. Among authors: obara t. Cold Spring Harb Symp Quant Biol. 1988;53 Pt 1:209-20. doi: 10.1101/sqb.1988.053.01.027. Cold Spring Harb Symp Quant Biol. 1988. PMID: 3151168 Review. No abstract available.

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