Valius M - Search Results

1

Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity.

Klinghoffer RA, Duckworth B, Valius M, Cantley L, Kazlauskas A. Klinghoffer RA, et al. Among authors: valius m. Mol Cell Biol. 1996 Oct;16(10):5905-14. doi: 10.1128/MCB.16.10.5905. Mol Cell Biol. 1996. PMID: 8816504 Free PMC article.

2

GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit.

Kazlauskas A, Kashishian A, Cooper JA, Valius M. Kazlauskas A, et al. Among authors: valius m. Mol Cell Biol. 1992 Jun;12(6):2534-44. doi: 10.1128/mcb.12.6.2534-2544.1992. Mol Cell Biol. 1992. PMID: 1375321 Free PMC article.

3

Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation.

Vaillancourt RR, Heasley LE, Zamarripa J, Storey B, Valius M, Kazlauskas A, Johnson GL. Vaillancourt RR, et al. Among authors: valius m. Mol Cell Biol. 1995 Jul;15(7):3644-53. doi: 10.1128/MCB.15.7.3644. Mol Cell Biol. 1995. PMID: 7540718 Free PMC article.

4

Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively.

Valius M, Bazenet C, Kazlauskas A. Valius M, et al. Mol Cell Biol. 1993 Jan;13(1):133-43. doi: 10.1128/mcb.13.1.133-143.1993. Mol Cell Biol. 1993. PMID: 7678051 Free PMC article.

5

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal.

Valius M, Kazlauskas A. Valius M, et al. Cell. 1993 Apr 23;73(2):321-34. doi: 10.1016/0092-8674(93)90232-f. Cell. 1993. PMID: 7682895

6

The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp.

Kazlauskas A, Feng GS, Pawson T, Valius M. Kazlauskas A, et al. Among authors: valius m. Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):6939-43. doi: 10.1073/pnas.90.15.6939. Proc Natl Acad Sci U S A. 1993. PMID: 7688466 Free PMC article.

7

The GTPase-activating protein of Ras suppresses platelet-derived growth factor beta receptor signaling by silencing phospholipase C-gamma 1.

Valius M, Secrist JP, Kazlauskas A. Valius M, et al. Mol Cell Biol. 1995 Jun;15(6):3058-71. doi: 10.1128/MCB.15.6.3058. Mol Cell Biol. 1995. PMID: 7760802 Free PMC article.

8

The platelet-derived growth factor beta receptor triggers multiple cytoplasmic signaling cascades that arrive at the nucleus as distinguishable inputs.

Montmayeur JP, Valius M, Vandenheede J, Kazlauskas A. Montmayeur JP, et al. Among authors: valius m. J Biol Chem. 1997 Dec 19;272(51):32670-8. doi: 10.1074/jbc.272.51.32670. J Biol Chem. 1997. PMID: 9405485 Free article.

9

PLC-gamma activation is required for PDGF-betaR-mediated mitogenesis and monocytic differentiation of myeloid progenitor cells.

Alimandi M, Heidaran MA, Gutkind JS, Zhang J, Ellmore N, Valius M, Kazlauskas A, Pierce JH, Li W. Alimandi M, et al. Among authors: valius m. Oncogene. 1997 Jul 31;15(5):585-93. doi: 10.1038/sj.onc.1201221. Oncogene. 1997. PMID: 9247312

10

Platelet-derived growth factor stimulates protein kinase D through the activation of phospholipase Cgamma and protein kinase C.

Van Lint J, Ni Y, Valius M, Merlevede W, Vandenheede JR. Van Lint J, et al. Among authors: valius m. J Biol Chem. 1998 Mar 20;273(12):7038-43. doi: 10.1074/jbc.273.12.7038. J Biol Chem. 1998. PMID: 9507012 Free article.

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