Nicholls PJ - Search Results

1

Anti-graft-versus-host disease effect of DT390-anti-CD3sFv, a single-chain Fv fusion immunotoxin specifically targeting the CD3 epsilon moiety of the T-cell receptor.

Vallera DA, Panoskaltsis-Mortari A, Jost C, Ramakrishnan S, Eide CR, Kreitman RJ, Nicholls PJ, Pennell C, Blazar BR. Vallera DA, et al. Among authors: nicholls pj. Blood. 1996 Sep 15;88(6):2342-53. Blood. 1996. PMID: 8822957 Free article.

2

Redirection of T cell-mediated cytotoxicity by a recombinant single-chain Fv molecule.

George AJ, Titus JA, Jost CR, Kurucz I, Perez P, Andrew SM, Nicholls PJ, Huston JS, Segal DM. George AJ, et al. Among authors: nicholls pj. J Immunol. 1994 Feb 15;152(4):1802-11. J Immunol. 1994. PMID: 8120389

3

Redirection of cellular cytotoxicity. A two-step approach using recombinant single-chain Fv molecules.

George AJ, Titus JA, Jost CR, Kurucz I, Perez P, Andrew SM, Nicholls PJ, Huston JS, Segal DM. George AJ, et al. Among authors: nicholls pj. Cell Biophys. 1995 Jun;26(3):153-65. doi: 10.1007/BF02791577. Cell Biophys. 1995. PMID: 8521448 Review.

4

Characterization of single-chain antibody (sFv)-toxin fusion proteins produced in vitro in rabbit reticulocyte lysate.

Nicholls PJ, Johnson VG, Andrew SM, Hoogenboom HR, Raus JC, Youle RJ. Nicholls PJ, et al. J Biol Chem. 1993 Mar 5;268(7):5302-8. J Biol Chem. 1993. PMID: 8444903 Free article.

5

An improved method for generating single-chain antibodies from hybridomas.

Nicholls PJ, Johnson VG, Blanford MD, Andrew SM. Nicholls PJ, et al. J Immunol Methods. 1993 Sep 27;165(1):81-91. doi: 10.1016/0022-1759(93)90109-k. J Immunol Methods. 1993. PMID: 8409471

6

Internalization of a Bacillus anthracis protective antigen-c-Myc fusion protein mediated by cell surface anti-c-Myc antibodies.

Varughese M, Chi A, Teixeira AV, Nicholls PJ, Keith JM, Leppla SH. Varughese M, et al. Among authors: nicholls pj. Mol Med. 1998 Feb;4(2):87-95. Mol Med. 1998. PMID: 9508786 Free PMC article.

7

Expression and characterization of recombinant human eosinophil-derived neurotoxin and eosinophil-derived neurotoxin-anti-transferrin receptor sFv.

Newton DL, Nicholls PJ, Rybak SM, Youle RJ. Newton DL, et al. Among authors: nicholls pj. J Biol Chem. 1994 Oct 28;269(43):26739-45. J Biol Chem. 1994. PMID: 7929408 Free article.

8

The role of proline 345 in diphtheria toxin translocation.

Johnson VG, Nicholls PJ, Habig WH, Youle RJ. Johnson VG, et al. Among authors: nicholls pj. J Biol Chem. 1993 Feb 15;268(5):3514-9. J Biol Chem. 1993. PMID: 8429026 Free article.

9

Identification of a single amino acid substitution in the diphtheria toxin A chain of CRM 228 responsible for the loss of enzymatic activity.

Johnson VG, Nicholls PJ. Johnson VG, et al. Among authors: nicholls pj. J Bacteriol. 1994 Aug;176(15):4766-9. doi: 10.1128/jb.176.15.4766-4769.1994. J Bacteriol. 1994. PMID: 8045910 Free PMC article.

10

Histidine 21 does not play a major role in diphtheria toxin catalysis.

Johnson VG, Nicholls PJ. Johnson VG, et al. Among authors: nicholls pj. J Biol Chem. 1994 Feb 11;269(6):4349-54. J Biol Chem. 1994. PMID: 8308004 Free article.

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