Woltering TJ - Search Results

1

Design and synthesis of C-linked fucosides as inhibitors of E-selectin.

Uchiyama T, Woltering TJ, Wong W, Lin CC, Kajimoto T, Takebayashi M, Weitz-Schmidt G, Asakura T, Noda M, Wong CH. Uchiyama T, et al. Among authors: woltering tj. Bioorg Med Chem. 1996 Jul;4(7):1149-65. doi: 10.1016/0968-0896(96)00127-7. Bioorg Med Chem. 1996. PMID: 8831987

2

Design, synthesis and biological evaluation of aryl-substituted sialyl Lewis X mimetics prepared via cross-metathesis of C-fucopeptides.

Huwe CM, Woltering TJ, Jiricek J, Weitz-Schmidt G, Wong CH. Huwe CM, et al. Among authors: woltering tj. Bioorg Med Chem. 1999 May;7(5):773-88. doi: 10.1016/s0968-0896(98)00245-4. Bioorg Med Chem. 1999. PMID: 10400330

3

BACE1 inhibitors: a head group scan on a series of amides.

Woltering TJ, Wostl W, Hilpert H, Rogers-Evans M, Pinard E, Mayweg A, Göbel M, Banner DW, Benz J, Travagli M, Pollastrini M, Marconi G, Gabellieri E, Guba W, Mauser H, Andreini M, Jacobsen H, Power E, Narquizian R. Woltering TJ, et al. Bioorg Med Chem Lett. 2013 Jul 15;23(14):4239-43. doi: 10.1016/j.bmcl.2013.05.003. Epub 2013 May 18. Bioorg Med Chem Lett. 2013. PMID: 23735744

4

Synthesis of heterocyclic enol ethers and their use as group 2 metabotropic glutamate receptor antagonists.

Kolczewski S, Adam G, Stadler H, Mutel V, Wichmann J, Woltering T. Kolczewski S, et al. Bioorg Med Chem Lett. 1999 Aug 2;9(15):2173-6. doi: 10.1016/s0960-894x(99)00346-7. Bioorg Med Chem Lett. 1999. PMID: 10465539

5

Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: part 2. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists.

Woltering TJ, Adam G, Wichmann J, Goetschi E, Kew JN, Knoflach F, Mutel V, Gatti S. Woltering TJ, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1091-5. doi: 10.1016/j.bmcl.2007.12.005. Epub 2007 Dec 8. Bioorg Med Chem Lett. 2008. PMID: 18096387

6

Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: new potent non-competitive metabotropic glutamate receptor 2/3 antagonists. Part 1.

Woltering TJ, Adam G, Alanine A, Wichmann J, Knoflach F, Mutel V, Gatti S. Woltering TJ, et al. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6811-5. doi: 10.1016/j.bmcl.2007.10.026. Epub 2007 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17964783

7

Synthesis and characterization of 1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: Part 3. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists.

Woltering TJ, Wichmann J, Goetschi E, Adam G, Kew JN, Knoflach F, Ballard TM, Huwyler J, Mutel V, Gatti S. Woltering TJ, et al. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2725-9. doi: 10.1016/j.bmcl.2008.02.076. Epub 2008 Mar 5. Bioorg Med Chem Lett. 2008. PMID: 18374569

8

Structure-activity relationships of substituted 5H-thiazolo[3,2-a]pyrimidines as group 2 metabotropic glutamate receptor antagonists.

Wichmann J, Adam G, Kolczewski S, Mutel V, Woltering T. Wichmann J, et al. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1573-6. doi: 10.1016/s0960-894x(99)00227-9. Bioorg Med Chem Lett. 1999. PMID: 10386938

9

A Real-World Perspective on Molecular Design.

Kuhn B, Guba W, Hert J, Banner D, Bissantz C, Ceccarelli S, Haap W, Körner M, Kuglstatter A, Lerner C, Mattei P, Neidhart W, Pinard E, Rudolph MG, Schulz-Gasch T, Woltering T, Stahl M. Kuhn B, et al. J Med Chem. 2016 May 12;59(9):4087-102. doi: 10.1021/acs.jmedchem.5b01875. Epub 2016 Feb 24. J Med Chem. 2016. PMID: 26878596

10

Synthesis and characterization of 1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: Part 4. In vivo active potent and selective non-competitive metabotropic glutamate receptor 2/3 antagonists.

Woltering TJ, Wichmann J, Goetschi E, Knoflach F, Ballard TM, Huwyler J, Gatti S. Woltering TJ, et al. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6969-74. doi: 10.1016/j.bmcl.2010.09.125. Epub 2010 Oct 21. Bioorg Med Chem Lett. 2010. PMID: 20971004

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