Costantino HR - Search Results

1

Strategies for stabilising tetanus toxoid towards the development of a single-dose tetanus vaccine.

Schwendeman SP, Costantino HR, Gupta RK, Tobio M, Chang AC, Alonso MJ, Siber GR, Langer R. Schwendeman SP, et al. Among authors: costantino hr. Dev Biol Stand. 1996;87:293-306. Dev Biol Stand. 1996. PMID: 8854030

2

Stabilization of tetanus and diphtheria toxoids against moisture-induced aggregation.

Schwendeman SP, Costantino HR, Gupta RK, Siber GR, Klibanov AM, Langer R. Schwendeman SP, et al. Among authors: costantino hr. Proc Natl Acad Sci U S A. 1995 Nov 21;92(24):11234-8. doi: 10.1073/pnas.92.24.11234. Proc Natl Acad Sci U S A. 1995. PMID: 7479971 Free PMC article.

3

The secondary structure and aggregation of lyophilized tetanus toxoid.

Costantino HR, Schwendeman SP, Griebenow K, Klibanov AM, Langer R. Costantino HR, et al. J Pharm Sci. 1996 Dec;85(12):1290-3. doi: 10.1021/js960148+. J Pharm Sci. 1996. PMID: 8961141

4

Deterioration of lyophilized pharmaceutical proteins.

Costantino HR, Schwendeman SP, Langer R, Klibanov AM. Costantino HR, et al. Biochemistry (Mosc). 1998 Mar;63(3):357-63. Biochemistry (Mosc). 1998. PMID: 9526132 Review.

5

Solid-phase aggregation of proteins under pharmaceutically relevant conditions.

Costantino HR, Langer R, Klibanov AM. Costantino HR, et al. J Pharm Sci. 1994 Dec;83(12):1662-9. doi: 10.1002/jps.2600831205. J Pharm Sci. 1994. PMID: 7891292 Review.

6

Moisture-induced aggregation of lyophilized insulin.

Costantino HR, Langer R, Klibanov AM. Costantino HR, et al. Pharm Res. 1994 Jan;11(1):21-9. doi: 10.1023/a:1018981208076. Pharm Res. 1994. PMID: 8140052

7

Aggregation of a lyophilized pharmaceutical protein, recombinant human albumin: effect of moisture and stabilization by excipients.

Costantino HR, Langer R, Klibanov AM. Costantino HR, et al. Biotechnology (N Y). 1995 May;13(5):493-6. doi: 10.1038/nbt0595-493. Biotechnology (N Y). 1995. PMID: 9634790

8

Fourier-transform infrared spectroscopic investigation of protein stability in the lyophilized form.

Costantino HR, Griebenow K, Mishra P, Langer R, Klibanov AM. Costantino HR, et al. Biochim Biophys Acta. 1995 Nov 15;1253(1):69-74. doi: 10.1016/0167-4838(95)00156-o. Biochim Biophys Acta. 1995. PMID: 7492602

9

On the pH memory of lyophilized compounds containing protein functional groups.

Costantino HR, Griebenow K, Langer R, Klibanov AM. Costantino HR, et al. Biotechnol Bioeng. 1997 Feb 5;53(3):345-8. doi: 10.1002/(SICI)1097-0290(19970205)53:3<345::AID-BIT14>3.0.CO;2-J. Biotechnol Bioeng. 1997. PMID: 18633990

10

Protein spray-freeze drying. Effect of atomization conditions on particle size and stability.

Costantino HR, Firouzabadian L, Hogeland K, Wu C, Beganski C, Carrasquillo KG, Córdova M, Griebenow K, Zale SE, Tracy MA. Costantino HR, et al. Pharm Res. 2000 Nov;17(11):1374-83. doi: 10.1023/a:1007570030368. Pharm Res. 2000. PMID: 11205730

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