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Synthesis and affinities for dopamine (D2) and 5-hydroxytryptamine (5-HT2A) receptors of 1-(benzoylpropyl)-4-(1-oxocycloalkyl-2-ethyl)-piperazines as cyclic butyrophenone derivatives.
Raviña E, Fueyo J, Masaguer CF, Negreira J, Cid J, Loza I, Honrubia A, Tristán H, G-Ferreiro T, Fontenla JA, Rosa E, Calleja JM, De Ceballos ML. Raviña E, et al. Among authors: tristan h. Chem Pharm Bull (Tokyo). 1996 Mar;44(3):534-41. doi: 10.1248/cpb.44.534. Chem Pharm Bull (Tokyo). 1996. PMID: 8882450
Conformationally constrained butyrophenones with mixed dopaminergic (D(2)) and serotoninergic (5-HT(2A), 5-HT(2C)) affinities: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and -thienocycloalkanones as putative atypical antipsychotics.
Raviña E, Negreira J, Cid J, Masaguer CF, Rosa E, Rivas ME, Fontenla JA, Loza MI, Tristán H, Cadavid MI, Sanz F, Lozoya E, Carotti A, Carrieri A. Raviña E, et al. Among authors: tristan h. J Med Chem. 1999 Jul 29;42(15):2774-97. doi: 10.1021/jm981094e. J Med Chem. 1999. PMID: 10425088
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