McGuire TF - Search Results

1

Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation.

McGuire TF, Qian Y, Vogt A, Hamilton AD, Sebti SM. McGuire TF, et al. J Biol Chem. 1996 Nov 1;271(44):27402-7. doi: 10.1074/jbc.271.44.27402. J Biol Chem. 1996. PMID: 8910319 Free article.

2

CAAX peptidomimetic FTI-244 decreases platelet-derived growth factor receptor tyrosine phosphorylation levels and inhibits stimulation of phosphatidylinositol 3-kinase but not mitogen-activated protein kinase.

McGuire TF, Qian Y, Blaskovich MA, Fossum RD, Sun J, Marlowe T, Corey SJ, Wathen SP, Vogt A, Hamilton AD, et al. McGuire TF, et al. Biochem Biophys Res Commun. 1995 Sep 5;214(1):295-303. doi: 10.1006/bbrc.1995.2287. Biochem Biophys Res Commun. 1995. PMID: 7669049

3

Lovastatin inhibits platelet-derived growth factor (PDGF) stimulation of phosphatidylinositol 3-kinase activity as well as association of p85 subunit to tyrosine-phosphorylated PDGF receptor.

McGuire TF, Corey SJ, Sebti SM. McGuire TF, et al. J Biol Chem. 1993 Oct 25;268(30):22227-30. J Biol Chem. 1993. PMID: 7693661 Free article.

4

Lovastatin inhibits the stimulation of mitogen-activated protein kinase by insulin in HIRcB fibroblasts.

Xu XQ, McGuire TF, Blaskovich MA, Sebti SM, Romero G. Xu XQ, et al. Among authors: mcguire tf. Arch Biochem Biophys. 1996 Feb 15;326(2):233-7. doi: 10.1006/abbi.1996.0070. Arch Biochem Biophys. 1996. PMID: 8611028

5

Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts.

Vogt A, Qian Y, McGuire TF, Hamilton AD, Sebti SM. Vogt A, et al. Among authors: mcguire tf. Oncogene. 1996 Nov 7;13(9):1991-9. Oncogene. 1996. PMID: 8934546

6

Geranylgeraniol potentiates lovastatin inhibition of oncogenic H-Ras processing and signaling while preventing cytotoxicity.

McGuire TF, Sebti SM. McGuire TF, et al. Oncogene. 1997 Jan 23;14(3):305-12. doi: 10.1038/sj.onc.1200819. Oncogene. 1997. PMID: 9018116

7

Inhibition of protein geranylgeranylation causes a superinduction of nitric-oxide synthase-2 by interleukin-1beta in vascular smooth muscle cells.

Finder JD, Litz JL, Blaskovich MA, McGuire TF, Qian Y, Hamilton AD, Davies P, Sebti SM. Finder JD, et al. Among authors: mcguire tf. J Biol Chem. 1997 May 23;272(21):13484-8. doi: 10.1074/jbc.272.21.13484. J Biol Chem. 1997. PMID: 9153192 Free article.

8

Lovastatin disrupts early events in insulin signaling: a potential mechanism of lovastatin's anti-mitogenic activity.

McGuire TF, Xu XQ, Corey SJ, Romero GG, Sebti SM. McGuire TF, et al. Biochem Biophys Res Commun. 1994 Oct 14;204(1):399-406. doi: 10.1006/bbrc.1994.2472. Biochem Biophys Res Commun. 1994. PMID: 7524501

9

Vitamin D(3)-induced apoptosis of murine squamous cell carcinoma cells. Selective induction of caspase-dependent MEK cleavage and up-regulation of MEKK-1.

McGuire TF, Trump DL, Johnson CS. McGuire TF, et al. J Biol Chem. 2001 Jul 13;276(28):26365-73. doi: 10.1074/jbc.M010101200. Epub 2001 Apr 30. J Biol Chem. 2001. PMID: 11331275 Free article.

10

Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines.

Miranda MB, McGuire TF, Johnson DE. Miranda MB, et al. Among authors: mcguire tf. Leukemia. 2002 Apr;16(4):683-92. doi: 10.1038/sj.leu.2402400. Leukemia. 2002. PMID: 11960350

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