Picarella DE - Search Results

1

Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells.

Grewal IS, Grewal KD, Wong FS, Picarella DE, Janeway CA Jr, Flavell RA. Grewal IS, et al. Among authors: picarella de. J Exp Med. 1996 Nov 1;184(5):1963-74. doi: 10.1084/jem.184.5.1963. J Exp Med. 1996. PMID: 8920883 Free PMC article.

2

Local production of human IL-6 promotes insulitis but retards the onset of insulin-dependent diabetes mellitus in non-obese diabetic mice.

DiCosmo BF, Picarella D, Flavell RA. DiCosmo BF, et al. Int Immunol. 1994 Dec;6(12):1829-37. doi: 10.1093/intimm/6.12.1829. Int Immunol. 1994. PMID: 7696203

3

Transgenic tumor necrosis factor (TNF)-alpha production in pancreatic islets leads to insulitis, not diabetes. Distinct patterns of inflammation in TNF-alpha and TNF-beta transgenic mice.

Picarella DE, Kratz A, Li CB, Ruddle NH, Flavell RA. Picarella DE, et al. J Immunol. 1993 May 1;150(9):4136-50. J Immunol. 1993. PMID: 7682590

4

Expression of transgene encoded TGF-beta in islets prevents autoimmune diabetes in NOD mice by a local mechanism.

Grewal IS, Grewal KD, Wong FS, Wang H, Picarella DE, Janeway CA Jr, Flavell RA. Grewal IS, et al. Among authors: picarella de. J Autoimmun. 2002 Aug-Sep;19(1-2):9-22. doi: 10.1006/jaut.2002.0599. J Autoimmun. 2002. PMID: 12367555

5

Probing the mechanism of TNF-alpha(cachectin)- and TNF-beta(lymphotoxin)-induced pancreatic inflammation with transgenic mice.

Ruddle NH, Picarella D, Kratz A, Li CB, Flavell RA. Ruddle NH, et al. Res Immunol. 1993 Jun;144(5):336-42. doi: 10.1016/s0923-2494(93)80077-c. Res Immunol. 1993. PMID: 8278655 Free article. Review. No abstract available.

6

Insulitis in transgenic mice expressing tumor necrosis factor beta (lymphotoxin) in the pancreas.

Picarella DE, Kratz A, Li CB, Ruddle NH, Flavell RA. Picarella DE, et al. Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10036-40. doi: 10.1073/pnas.89.21.10036. Proc Natl Acad Sci U S A. 1992. PMID: 1279667 Free PMC article.

7

Costimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumor necrosis factor alpha leads to autoimmunity in transgenic mice.

Guerder S, Picarella DE, Linsley PS, Flavell RA. Guerder S, et al. Among authors: picarella de. Proc Natl Acad Sci U S A. 1994 May 24;91(11):5138-42. doi: 10.1073/pnas.91.11.5138. Proc Natl Acad Sci U S A. 1994. PMID: 7515187 Free PMC article.

8

Expression of interleukin-6 by airway epithelial cells. Effects on airway inflammation and hyperreactivity in transgenic mice.

DiCosmo B, Geba G, Picarella D, Elias JA, Rankin JA, Stripp B, Whitsett JA, Flavell RA. DiCosmo B, et al. Chest. 1995 Mar;107(3 Suppl):131S. doi: 10.1378/chest.107.3_supplement.131s. Chest. 1995. PMID: 7874993 No abstract available.

9

Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity.

DiCosmo BF, Geba GP, Picarella D, Elias JA, Rankin JA, Stripp BR, Whitsett JA, Flavell RA. DiCosmo BF, et al. J Clin Invest. 1994 Nov;94(5):2028-35. doi: 10.1172/JCI117556. J Clin Invest. 1994. PMID: 7962549 Free PMC article.

10

Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity.

Rankin JA, Picarella DE, Geba GP, Temann UA, Prasad B, DiCosmo B, Tarallo A, Stripp B, Whitsett J, Flavell RA. Rankin JA, et al. Among authors: picarella de. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7821-5. doi: 10.1073/pnas.93.15.7821. Proc Natl Acad Sci U S A. 1996. PMID: 8755560 Free PMC article.

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