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The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways.
Carroll M, Tomasson MH, Barker GF, Golub TR, Gilliland DG. Carroll M, et al. Among authors: tomasson mh. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14845-50. doi: 10.1073/pnas.93.25.14845. Proc Natl Acad Sci U S A. 1996. PMID: 8962143 Free PMC article.
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9.
Dash AB, Williams IR, Kutok JL, Tomasson MH, Anastasiadou E, Lindahl K, Li S, Van Etten RA, Borrow J, Housman D, Druker B, Gilliland DG. Dash AB, et al. Among authors: tomasson mh. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7622-7. doi: 10.1073/pnas.102583199. Proc Natl Acad Sci U S A. 2002. PMID: 12032333 Free PMC article.
The TEL gene and human leukemia.
Golub TR, McLean T, Stegmaier K, Carroll M, Tomasson M, Gilliland DG. Golub TR, et al. Biochim Biophys Acta. 1996 Aug 8;1288(1):M7-10. doi: 10.1016/0304-419x(96)00015-7. Biochim Biophys Acta. 1996. PMID: 8764840 Review. No abstract available.
The Jak2V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes.
Wernig G, Gonneville JR, Crowley BJ, Rodrigues MS, Reddy MM, Hudon HE, Walz C, Reiter A, Podar K, Royer Y, Constantinescu SN, Tomasson MH, Griffin JD, Gilliland DG, Sattler M. Wernig G, et al. Among authors: tomasson mh. Blood. 2008 Apr 1;111(7):3751-9. doi: 10.1182/blood-2007-07-102186. Epub 2008 Jan 23. Blood. 2008. PMID: 18216297 Free PMC article.
Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes.
Schwaller J, Frantsve J, Aster J, Williams IR, Tomasson MH, Ross TS, Peeters P, Van Rompaey L, Van Etten RA, Ilaria R Jr, Marynen P, Gilliland DG. Schwaller J, et al. Among authors: tomasson mh. EMBO J. 1998 Sep 15;17(18):5321-33. doi: 10.1093/emboj/17.18.5321. EMBO J. 1998. PMID: 9736611 Free PMC article.
96 results