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Second-site proviral enhancer alterations in lymphomas induced by enhancer mutants of SL3-3 murine leukemia virus: negative effect of nuclear factor 1 binding site.
Ethelberg S, Hallberg B, Lovmand J, Schmidt J, Luz A, Grundström T, Pedersen FS. Ethelberg S, et al. Among authors: schmidt j. J Virol. 1997 Feb;71(2):1196-206. doi: 10.1128/JVI.71.2.1196-1206.1997. J Virol. 1997. PMID: 8995642 Free PMC article.
Previously, mutation of binding sites in the U3 repeat region for the AML1 transcription factor family (also known as core binding factor [CBF], polyomavirus enhancer binding protein 2 [PEBP2], and SL3-3 enhancer factor 1 [SEF1]) were found to strongly reduce the pathogenicity of …
Previously, mutation of binding sites in the U3 repeat region for the AML1 transcription factor family (also known as core binding factor [C …
Mutation of all Runx (AML1/core) sites in the enhancer of T-lymphomagenic SL3-3 murine leukemia virus unmasks a significant potential for myeloid leukemia induction and favors enhancer evolution toward induction of other disease patterns.
Sørensen KD, Quintanilla-Martinez L, Kunder S, Schmidt J, Pedersen FS. Sørensen KD, et al. Among authors: schmidt j. J Virol. 2004 Dec;78(23):13216-31. doi: 10.1128/JVI.78.23.13216-13231.2004. J Virol. 2004. PMID: 15542674 Free PMC article.
Using inbred NMRI mice, it was previously reported that a mutant of SL3-3 with all enhancer Runx (AML1/core) sites disrupted by 3-bp mutations (SL3-3dm) induces predominantly non-T-cell tumors with severely extended latency (S. Ethelberg, J. Lovmand, J. Schmidt
Using inbred NMRI mice, it was previously reported that a mutant of SL3-3 with all enhancer Runx (AML1/core) sites disrupted by 3-bp mutatio …
Analysis of wild-type and mutant SL3-3 murine leukemia virus insertions in the c-myc promoter during lymphomagenesis reveals target site hot spots, virus-dependent patterns, and frequent error-prone gap repair.
Nielsen AA, Sørensen AB, Schmidt J, Pedersen FS. Nielsen AA, et al. Among authors: schmidt j. J Virol. 2005 Jan;79(1):67-78. doi: 10.1128/JVI.79.1.67-78.2005. J Virol. 2005. PMID: 15596802 Free PMC article.
Previously, our laboratory reported on a deletion mutant of SL3-3 that induces T-cell tumors faster than the wild-type virus (S. Ethelberg, A. B. Sorensen, J. Schmidt, A. Luz, and F. S. Pedersen, J. Virol. 71:9796-9799, 1997). PCR analyses of proviral integra …
Previously, our laboratory reported on a deletion mutant of SL3-3 that induces T-cell tumors faster than the wild-type virus (S. Ethelberg, …
6,617 results