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Control of conformational equilibria in the human B2 bradykinin receptor. Modeling of nonpeptidic ligand action and comparison to the rhodopsin structure.
Marie J, Richard E, Pruneau D, Paquet JL, Siatka C, Larguier R, Poncé C, Vassault P, Groblewski T, Maigret B, Bonnafous JC. Marie J, et al. Among authors: groblewski t. J Biol Chem. 2001 Nov 2;276(44):41100-11. doi: 10.1074/jbc.M104875200. Epub 2001 Aug 8. J Biol Chem. 2001. PMID: 11495910 Free article.
Discovery of spirofused piperazine and diazepane amides as selective histamine-3 antagonists with in vivo efficacy in a mouse model of cognition.
Brown DG, Bernstein PR, Griffin A, Wesolowski S, Labrecque D, Tremblay MC, Sylvester M, Mauger R, Edwards PD, Throner SR, Folmer JJ, Cacciola J, Scott C, Lazor LA, Pourashraf M, Santhakumar V, Potts WM, Sydserff S, Giguère P, Lévesque C, Dasser M, Groblewski T. Brown DG, et al. Among authors: groblewski t. J Med Chem. 2014 Feb 13;57(3):733-58. doi: 10.1021/jm4014828. Epub 2014 Jan 27. J Med Chem. 2014. PMID: 24410637
N-Methyl-3-(tetrahydro-2H-pyran-4-yl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamides as a novel class of cannabinoid receptors agonists with low CNS penetration.
Wei Z, Yang H, Liu Z, Tremblay M, Johnstone S, Béha S, Yue SY, Srivastava S, Tomaszewski MJ, Brown W, Walpole C, St-Onge S, Lessard E, Archambault AJ, Groblewski T, Pagé D. Wei Z, et al. Among authors: groblewski t. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3884-9. doi: 10.1016/j.bmcl.2012.04.128. Epub 2012 May 4. Bioorg Med Chem Lett. 2012. PMID: 22607668
19 results