Hakimi J - Search Results

1

A phase I trial of humanized anti-interleukin 2 receptor antibody in renal transplantation.

Vincenti F, Lantz M, Birnbaum J, Garovoy M, Mould D, Hakimi J, Nieforth K, Light S. Vincenti F, et al. Among authors: hakimi j. Transplantation. 1997 Jan 15;63(1):33-8. doi: 10.1097/00007890-199701150-00007. Transplantation. 1997. PMID: 9000657 Clinical Trial.

2

Successful in vivo blockade of CD25 (high-affinity interleukin 2 receptor) on T cells by administration of humanized anti-Tac antibody to patients with psoriasis.

Krueger JG, Walters IB, Miyazawa M, Gilleaudeau P, Hakimi J, Light S, Sherr A, Gottlieb AB. Krueger JG, et al. Among authors: hakimi j. J Am Acad Dermatol. 2000 Sep;43(3):448-58. doi: 10.1067/mjd.2000.106515. J Am Acad Dermatol. 2000. PMID: 10954656 Clinical Trial.

3

Daclizumab rapidly saturates interleukin-2 receptor-alpha (CD25) on lymph node lymphocytes in children.

Savo AM, Book BK, Henson S, Hakimi J, Pescovitz MD. Savo AM, et al. Among authors: hakimi j. Transplant Proc. 1999 Feb-Mar;31(1-2):1182-3. doi: 10.1016/s0041-1345(98)01955-1. Transplant Proc. 1999. PMID: 10083528 Clinical Trial. No abstract available.

4

Anti-Tac-H, a humanized antibody to the interleukin 2 receptor, prolongs primate cardiac allograft survival.

Brown PS Jr, Parenteau GL, Dirbas FM, Garsia RJ, Goldman CK, Bukowski MA, Junghans RP, Queen C, Hakimi J, Benjamin WR, et al. Brown PS Jr, et al. Among authors: hakimi j. Proc Natl Acad Sci U S A. 1991 Apr 1;88(7):2663-7. doi: 10.1073/pnas.88.7.2663. Proc Natl Acad Sci U S A. 1991. PMID: 2011577 Free PMC article.

5

Humanized Mik beta 1, a humanized antibody to the IL-2 receptor beta-chain that acts synergistically with humanized anti-TAC.

Hakimi J, Ha VC, Lin P, Campbell E, Gately MK, Tsudo M, Payne PW, Waldmann TA, Grant AJ, Tsien WH, et al. Hakimi J, et al. J Immunol. 1993 Jul 15;151(2):1075-85. J Immunol. 1993. PMID: 8335891

6

Humanized antibodies against the alpha-chain of the IL-2 receptor and against the beta-chain shared by the IL-2 and IL-15 receptors in a monkey uveitis model of autoimmune diseases.

Guex-Crosier Y, Raber J, Chan CC, Kriete MS, Benichou J, Pilson RS, Kerwin JA, Waldmann TA, Hakimi J, Roberge FG. Guex-Crosier Y, et al. Among authors: hakimi j. J Immunol. 1997 Jan 1;158(1):452-8. J Immunol. 1997. PMID: 8977222

7

Humanized antibody directed to the IL-2 receptor beta-chain prolongs primate cardiac allograft survival.

Tinubu SA, Hakimi J, Kondas JA, Bailon P, Familletti PC, Spence C, Crittenden MD, Parenteau GL, Dirbas FM, Tsudo M, et al. Tinubu SA, et al. Among authors: hakimi j. J Immunol. 1994 Nov 1;153(9):4330-8. J Immunol. 1994. PMID: 7930631

8

Reduced immunogenicity and improved pharmacokinetics of humanized anti-Tac in cynomolgus monkeys.

Hakimi J, Chizzonite R, Luke DR, Familletti PC, Bailon P, Kondas JA, Pilson RS, Lin P, Weber DV, Spence C, et al. Hakimi J, et al. J Immunol. 1991 Aug 15;147(4):1352-9. J Immunol. 1991. PMID: 1869828

9

Prophylactic and therapeutic effects of a humanized monoclonal antibody against the IL-2 receptor (DACLIZUMAB) on collagen-induced arthritis (CIA) in rhesus monkeys.

Brok HP, Tekoppele JM, Hakimi J, Kerwin JA, Nijenhuis EM, De Groot CW, Bontrop RE, 't Hart BA. Brok HP, et al. Among authors: hakimi j. Clin Exp Immunol. 2001 Apr;124(1):134-41. doi: 10.1046/j.1365-2249.2001.01487.x. Clin Exp Immunol. 2001. PMID: 11359452 Free PMC article.

10

Bispecific humanized anti-IL-2 receptor alpha beta antibodies inhibitory for both IL-2- and IL-15-mediated proliferation.

Pilson RS, Levin W, Desai B, Reik LM, Lin P, Korkmaz-Duffy E, Campbell E, Tso JY, Kerwin JA, Hakimi J. Pilson RS, et al. Among authors: hakimi j. J Immunol. 1997 Aug 1;159(3):1543-56. J Immunol. 1997. PMID: 9233654

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