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An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma.
Pannu J, Gore-Hyer E, Yamanaka M, Smith EA, Rubinchik S, Dong JY, Jablonska S, Blaszczyk M, Trojanowska M. Pannu J, et al. Among authors: smith ea. Arthritis Rheum. 2004 May;50(5):1566-77. doi: 10.1002/art.20225. Arthritis Rheum. 2004. PMID: 15146427 Free article.
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