Beale G - Search Results

1

Protein expression of the epsilon subspecies of protein kinase C ceases as Swiss 3T6 fibroblasts increase in cell density even though message for the protein is still present.

Littlebury P, Watson J, Williams T, Beale G, Rumsby M. Littlebury P, et al. Among authors: beale g. FEBS Lett. 1997 Jan 6;400(3):304-8. doi: 10.1016/s0014-5793(96)01394-4. FEBS Lett. 1997. PMID: 9009219 Free article.

2

Ro31-8220 inhibits protein kinase C to block the phorbol ester-stimulated release of choline- and ethanolamine-metabolites from C6 glioma cells: p70 S6 kinase and MAPKAP kinase-1beta do not function downstream of PKC in activating PLD.

Morreale A, Mallon B, Beale G, Watson J, Rumsby M. Morreale A, et al. Among authors: beale g. FEBS Lett. 1997 Nov 3;417(1):38-42. doi: 10.1016/s0014-5793(97)01252-0. FEBS Lett. 1997. PMID: 9395070 Free article.

3

Signalling pathways regulating the dephosphorylation of Ser729 in the hydrophobic domain of protein kinase Cepsilon upon cell passage.

England K, Watson J, Beale G, Warner M, Cross J, Rumsby M. England K, et al. Among authors: beale g. J Biol Chem. 2001 Mar 30;276(13):10437-42. doi: 10.1074/jbc.M009421200. Epub 2000 Dec 19. J Biol Chem. 2001. PMID: 11121415 Free article.

4

The synergistic interaction of MEK and PI3K inhibitors is modulated by mTOR inhibition.

Haagensen EJ, Kyle S, Beale GS, Maxwell RJ, Newell DR. Haagensen EJ, et al. Among authors: beale gs. Br J Cancer. 2012 Apr 10;106(8):1386-94. doi: 10.1038/bjc.2012.70. Epub 2012 Mar 13. Br J Cancer. 2012. PMID: 22415236 Free PMC article.

5

Combined PI3K and CDK2 inhibition induces cell death and enhances in vivo antitumour activity in colorectal cancer.

Beale G, Haagensen EJ, Thomas HD, Wang LZ, Revill CH, Payne SL, Golding BT, Hardcastle IR, Newell DR, Griffin RJ, Cano C. Beale G, et al. Br J Cancer. 2016 Sep 6;115(6):682-90. doi: 10.1038/bjc.2016.238. Epub 2016 Aug 16. Br J Cancer. 2016. PMID: 27529512 Free PMC article.

6

Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines.

Peasland A, Wang LZ, Rowling E, Kyle S, Chen T, Hopkins A, Cliby WA, Sarkaria J, Beale G, Edmondson RJ, Curtin NJ. Peasland A, et al. Among authors: beale g. Br J Cancer. 2011 Jul 26;105(3):372-81. doi: 10.1038/bjc.2011.243. Epub 2011 Jul 5. Br J Cancer. 2011. PMID: 21730979 Free PMC article.

7

Regioselective sulfamoylation at low temperature enables concise syntheses of putative small molecule inhibitors of sulfatases.

Miller DC, Carbain B, Beale GS, Alhasan SF, Reeves HL, Baisch U, Newell DR, Golding BT, Griffin RJ. Miller DC, et al. Among authors: beale gs. Org Biomol Chem. 2015 May 14;13(18):5279-84. doi: 10.1039/c5ob00211g. Org Biomol Chem. 2015. PMID: 25858034

8

Sulfatase-2: a prognostic biomarker and candidate therapeutic target in patients with pancreatic ductal adenocarcinoma.

Alhasan SF, Haugk B, Ogle LF, Beale GS, Long A, Burt AD, Tiniakos D, Televantou D, Coxon F, Newell DR, Charnley R, Reeves HL. Alhasan SF, et al. Among authors: beale gs. Br J Cancer. 2016 Sep 27;115(7):797-804. doi: 10.1038/bjc.2016.264. Epub 2016 Aug 25. Br J Cancer. 2016. PMID: 27560551 Free PMC article.

9

Design and synthesis of biphenyl and biphenyl ether inhibitors of sulfatases.

Reuillon T, Alhasan SF, Beale GS, Bertoli A, Brennan A, Cano C, Reeves HL, Newell DR, Golding BT, Miller DC, Griffin RJ. Reuillon T, et al. Among authors: beale gs. Chem Sci. 2016 Apr 21;7(4):2821-2826. doi: 10.1039/c5sc03612g. Epub 2016 Jan 11. Chem Sci. 2016. PMID: 28660059 Free PMC article.

10

AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease.

Beale G, Chattopadhyay D, Gray J, Stewart S, Hudson M, Day C, Trerotoli P, Giannelli G, Manas D, Reeves H. Beale G, et al. BMC Cancer. 2008 Jul 18;8:200. doi: 10.1186/1471-2407-8-200. BMC Cancer. 2008. PMID: 18638391 Free PMC article.

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