Grosveld F - Search Results

1

Correction of the X-linked immunodeficiency phenotype by transgenic expression of human Bruton tyrosine kinase under the control of the class II major histocompatibility complex Ea locus control region.

Drabek D, Raguz S, De Wit TP, Dingjan GM, Savelkoul HF, Grosveld F, Hendriks RW. Drabek D, et al. Among authors: grosveld f. Proc Natl Acad Sci U S A. 1997 Jan 21;94(2):610-5. doi: 10.1073/pnas.94.2.610. Proc Natl Acad Sci U S A. 1997. PMID: 9012832 Free PMC article.

2

The chicken beta/epsilon-globin enhancer directs autonomously regulated, high-level expression of the chicken epsilon-globin gene in transgenic mice.

Foley KP, Pruzina S, Winick JD, Engel JD, Grosveld F, Fraser P. Foley KP, et al. Among authors: grosveld f. Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7252-6. doi: 10.1073/pnas.91.15.7252. Proc Natl Acad Sci U S A. 1994. PMID: 8041775 Free PMC article.

3

Role of the duplicated CCAAT box region in gamma-globin gene regulation and hereditary persistence of fetal haemoglobin.

Ronchi A, Berry M, Raguz S, Imam A, Yannoutsos N, Ottolenghi S, Grosveld F, Dillon N. Ronchi A, et al. Among authors: grosveld f. EMBO J. 1996 Jan 2;15(1):143-9. EMBO J. 1996. PMID: 8598197 Free PMC article.

4

Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage.

Hendriks RW, de Bruijn MF, Maas A, Dingjan GM, Karis A, Grosveld F. Hendriks RW, et al. Among authors: grosveld f. EMBO J. 1996 Sep 16;15(18):4862-72. EMBO J. 1996. PMID: 8890160 Free PMC article.

5

The human beta-globin locus control region confers an early embryonic erythroid-specific expression pattern to a basic promoter driving the bacterial lacZ gene.

Tewari R, Gillemans N, Harper A, Wijgerde M, Zafarana G, Drabek D, Grosveld F, Philipsen S. Tewari R, et al. Among authors: grosveld f. Development. 1996 Dec;122(12):3991-9. doi: 10.1242/dev.122.12.3991. Development. 1996. PMID: 9012519

6

The expression of bacterial nitroreductase in transgenic mice results in specific cell killing by the prodrug CB1954.

Drabek D, Guy J, Craig R, Grosveld F. Drabek D, et al. Among authors: grosveld f. Gene Ther. 1997 Feb;4(2):93-100. doi: 10.1038/sj.gt.3300366. Gene Ther. 1997. PMID: 9081711

7

The X-linked immunodeficiency defect in the mouse is corrected by expression of human Bruton's tyrosine kinase from a yeast artificial chromosome transgene.

Maas A, Dingjan GM, Savelkoul HF, Kinnon C, Grosveld F, Hendriks RW. Maas A, et al. Among authors: grosveld f. Eur J Immunol. 1997 Sep;27(9):2180-7. doi: 10.1002/eji.1830270910. Eur J Immunol. 1997. PMID: 9341757

8

Microinjection of cre recombinase RNA induces site-specific recombination of a transgene in mouse oocytes.

de Wit T, Drabek D, Grosveld F. de Wit T, et al. Among authors: grosveld f. Nucleic Acids Res. 1998 Jan 15;26(2):676-8. doi: 10.1093/nar/26.2.676. Nucleic Acids Res. 1998. PMID: 9421533 Free PMC article.

9

The dynamics of globin gene expression and gene therapy vectors.

Grosveld F, De Boer E, Dillon N, Gribnau J, Milot E, Trimborn T, Wijgerde M, Fraser P. Grosveld F, et al. Ann N Y Acad Sci. 1998 Jun 30;850:18-27. doi: 10.1111/j.1749-6632.1998.tb10458.x. Ann N Y Acad Sci. 1998. PMID: 9705737 Review.

10

Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase.

Dingjan GM, Maas A, Nawijn MC, Smit L, Voerman JS, Grosveld F, Hendriks RW. Dingjan GM, et al. Among authors: grosveld f. EMBO J. 1998 Sep 15;17(18):5309-20. doi: 10.1093/emboj/17.18.5309. EMBO J. 1998. PMID: 9736610 Free PMC article.

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