Chan SL - Search Results

1

1-(5-Isoquinolinesulfonyl)-2-methylpiperazine induces apoptosis in human neuroblastoma cells, SH-SY5Y, through a p53-dependent pathway.

Ronca F, Chan SL, Yu VC. Ronca F, et al. Among authors: chan sl. J Biol Chem. 1997 Feb 14;272(7):4252-60. doi: 10.1074/jbc.272.7.4252. J Biol Chem. 1997. PMID: 9020141 Free article.

2

Identification of chelerythrine as an inhibitor of BclXL function.

Chan SL, Lee MC, Tan KO, Yang LK, Lee AS, Flotow H, Fu NY, Butler MS, Soejarto DD, Buss AD, Yu VC. Chan SL, et al. J Biol Chem. 2003 Jun 6;278(23):20453-6. doi: 10.1074/jbc.C300138200. Epub 2003 Apr 17. J Biol Chem. 2003. PMID: 12702731 Free article.

3

Chelerythrine induces apoptosis through a Bax/Bak-independent mitochondrial mechanism.

Wan KF, Chan SL, Sukumaran SK, Lee MC, Yu VC. Wan KF, et al. Among authors: chan sl. J Biol Chem. 2008 Mar 28;283(13):8423-33. doi: 10.1074/jbc.M707687200. Epub 2008 Jan 29. J Biol Chem. 2008. PMID: 18230621 Free PMC article.

4

F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis.

Chan SL, Tan KO, Zhang L, Yee KS, Ronca F, Chan MY, Yu VC. Chan SL, et al. Among authors: chan my. J Biol Chem. 1999 Nov 5;274(45):32461-8. doi: 10.1074/jbc.274.45.32461. J Biol Chem. 1999. PMID: 10542291 Free article.

5

The Caenorhabditis elegans sex determination protein FEM-1 is a CED-3 substrate that associates with CED-4 and mediates apoptosis in mammalian cells.

Chan SL, Yee KS, Tan KM, Yu VC. Chan SL, et al. J Biol Chem. 2000 Jun 16;275(24):17925-8. doi: 10.1074/jbc.C000146200. J Biol Chem. 2000. PMID: 10764728 Free article.

6

MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains.

Tan KO, Tan KM, Chan SL, Yee KS, Bevort M, Ang KC, Yu VC. Tan KO, et al. Among authors: chan sl. J Biol Chem. 2001 Jan 26;276(4):2802-7. doi: 10.1074/jbc.M008955200. Epub 2000 Nov 1. J Biol Chem. 2001. PMID: 11060313 Free article.

7

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis.

Tan KM, Chan SL, Tan KO, Yu VC. Tan KM, et al. Among authors: chan sl. J Biol Chem. 2001 Nov 23;276(47):44193-202. doi: 10.1074/jbc.M105880200. Epub 2001 Sep 14. J Biol Chem. 2001. PMID: 11559703 Free article.

8

Proteins of the bcl-2 family in apoptosis signalling: from mechanistic insights to therapeutic opportunities.

Chan SL, Yu VC. Chan SL, et al. Clin Exp Pharmacol Physiol. 2004 Mar;31(3):119-28. doi: 10.1111/j.1440-1681.2004.03975.x. Clin Exp Pharmacol Physiol. 2004. PMID: 15008953 Review.

9

MAP-1 is a mitochondrial effector of Bax.

Tan KO, Fu NY, Sukumaran SK, Chan SL, Kang JH, Poon KL, Chen BS, Yu VC. Tan KO, et al. Among authors: chan sl. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14623-8. doi: 10.1073/pnas.0503524102. Epub 2005 Sep 30. Proc Natl Acad Sci U S A. 2005. PMID: 16199525 Free PMC article.

10

Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft.

Zhang YH, Bhunia A, Wan KF, Lee MC, Chan SL, Yu VC, Mok YK. Zhang YH, et al. Among authors: chan sl. J Mol Biol. 2006 Dec 1;364(3):536-49. doi: 10.1016/j.jmb.2006.09.023. Epub 2006 Sep 14. J Mol Biol. 2006. PMID: 17011577

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