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Novel C-2 substituted carbapenem derivatives. Part II. Synthesis and structure-activity relationships of isoxazolin-2-yl, isoxazolidin-2-yl and 2-pyrazolin-2-yl carbapenems generated using 1,3-dipolar cycloaddition chemistry.
Burton G, Clarke GJ, Douglas JD, Eglington AJ, Frydrych CH, Hinks JD, Hird NW, Hunt E, Moss SF, Naylor A, Nicholson NH, Pearson MJ. Burton G, et al. Among authors: pearson mj. J Antibiot (Tokyo). 1996 Dec;49(12):1266-74. doi: 10.7164/antibiotics.49.1266. J Antibiot (Tokyo). 1996. PMID: 9031673 Free article.
Novel C-2 substituted carbapenem derivatives. Part IV. Synthesis and biological activity of five membered heteroaromatic derivatives.
Branch CL, Burton G, Clarke GJ, Coulton S, Douglas JD, Eglington AJ, Guest AW, Hinks JD, Hird NW, Holland RK, Hunt E, Knott SJ, Moss SF, Naylor A, Pearson MJ, Takle AK. Branch CL, et al. Among authors: pearson mj. J Antibiot (Tokyo). 1998 Feb;51(2):210-20. doi: 10.7164/antibiotics.51.210. J Antibiot (Tokyo). 1998. PMID: 9544943 Free article.
Structure-activity relationships within a series of C(7)-substitutedoxyiminocephalosporins containing the C(3)-methylaminopyridiniumthiomethyl substituent. Synthesis and biological properties of BRL 57342 and some close analogues.
Adams RG, Brain EG, Branch CL, Guest AW, Harrington FP, Mizen L, Neale JE, Pearson MJ, Simpson IN, Smulders H, et al. Adams RG, et al. Among authors: pearson mj. J Antibiot (Tokyo). 1995 May;48(5):417-24. doi: 10.7164/antibiotics.48.417. J Antibiot (Tokyo). 1995. PMID: 7797444 Free article.
Antibacterial activity of some (C2)-heterobicyclyl carbapenem derivatives.
Burton G, Coulton S, Harrington FP, Hinks JD, Holland RK, Hunt E, Pearson MJ. Burton G, et al. Among authors: pearson mj. J Antibiot (Tokyo). 1998 Jun;51(6):599-601. doi: 10.7164/antibiotics.51.599. J Antibiot (Tokyo). 1998. PMID: 9711227 Free article. No abstract available.
Pleuromutilins. Part 1. The identification of novel mutilin 14-carbamates.
Brooks G, Burgess W, Colthurst D, Hinks JD, Hunt E, Pearson MJ, Shea B, Takle AK, Wilson JM, Woodnutt G. Brooks G, et al. Among authors: pearson mj. Bioorg Med Chem. 2001 May;9(5):1221-31. doi: 10.1016/s0968-0896(00)00338-2. Bioorg Med Chem. 2001. PMID: 11377180
123 results