Nguyen D - Search Results

1

Structure-based design of substituted diphenyl sulfones and sulfoxides as lipophilic inhibitors of thymidylate synthase.

Jones TR, Webber SE, Varney MD, Reddy MR, Lewis KK, Kathardekar V, Mazdiyasni H, Deal J, Nguyen D, Welsh KM, Webber S, Johnston A, Matthews DA, Smith WW, Janson CA, Bacquet RJ, Howland EF, Booth CL, Herrmann SM, Ward RW, White J, Bartlett CA, Morse CA. Jones TR, et al. Among authors: nguyen d. J Med Chem. 1997 Feb 28;40(5):677-83. doi: 10.1021/jm960613f. J Med Chem. 1997. PMID: 9057854

2

Design and synthesis of novel 6,7-imidazotetrahydroquinoline inhibitors of thymidylate synthase using iterative protein crystal structure analysis.

Reich SH, Fuhry MA, Nguyen D, Pino MJ, Welsh KM, Webber S, Janson CA, Jordan SR, Matthews DA, Smith WW, et al. Reich SH, et al. Among authors: nguyen d. J Med Chem. 1992 Mar 6;35(5):847-58. doi: 10.1021/jm00083a007. J Med Chem. 1992. PMID: 1548676

3

Bis tertiary amide inhibitors of the HIV-1 protease generated via protein structure-based iterative design.

Melnick M, Reich SH, Lewis KK, Mitchell LJ Jr, Nguyen D, Trippe AJ, Dawson H, Davies JF 2nd, Appelt K, Wu BW, Musick L, Gehlhaar DK, Webber S, Shetty B, Kosa M, Kahil D, Andrada D. Melnick M, et al. Among authors: nguyen d. J Med Chem. 1996 Jul 5;39(14):2795-811. doi: 10.1021/jm960092w. J Med Chem. 1996. PMID: 8709110

4

Protein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease.

Reich SH, Melnick M, Davies JF 2nd, Appelt K, Lewis KK, Fuhry MA, Pino M, Trippe AJ, Nguyen D, Dawson H, et al. Reich SH, et al. Among authors: nguyen d. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3298-302. doi: 10.1073/pnas.92.8.3298. Proc Natl Acad Sci U S A. 1995. PMID: 7724556 Free PMC article.

5

Human semaphorin K1 is glycosylphosphatidylinositol-linked and defines a new subfamily of viral-related semaphorins.

Xu X, Ng S, Wu ZL, Nguyen D, Homburger S, Seidel-Dugan C, Ebens A, Luo Y. Xu X, et al. Among authors: nguyen d. J Biol Chem. 1998 Aug 28;273(35):22428-34. doi: 10.1074/jbc.273.35.22428. J Biol Chem. 1998. PMID: 9712866 Free article.

6

Structures of two novel crystal forms of Naja naja naja phospholipase A2 lacking Ca2+ reveal trimeric packing.

Segelke BW, Nguyen D, Chee R, Xuong NH, Dennis EA. Segelke BW, et al. Among authors: nguyen d. J Mol Biol. 1998 May 29;279(1):223-32. doi: 10.1006/jmbi.1998.1759. J Mol Biol. 1998. PMID: 9636712

7

Ligand cross-reactivity within the protease-activated receptor family.

Blackhart BD, Emilsson K, Nguyen D, Teng W, Martelli AJ, Nystedt S, Sundelin J, Scarborough RM. Blackhart BD, et al. Among authors: nguyen d. J Biol Chem. 1996 Jul 12;271(28):16466-71. doi: 10.1074/jbc.271.28.16466. J Biol Chem. 1996. PMID: 8663335 Free article.

8

Inducible nitric oxide synthase-mediated alteration of mitochondrial OPA1 expression in ocular hypertensive rats.

Dai Y, Weinreb RN, Kim KY, Nguyen D, Park S, Sun X, Lindsey JD, Ellisman MH, Ju WK. Dai Y, et al. Among authors: nguyen d. Invest Ophthalmol Vis Sci. 2011 Apr 16;52(5):2468-76. doi: 10.1167/iovs.10-5873. Invest Ophthalmol Vis Sci. 2011. PMID: 21220562 Free PMC article.

9

A selective inhibitor of drp1, mdivi-1, increases retinal ganglion cell survival in acute ischemic mouse retina.

Park SW, Kim KY, Lindsey JD, Dai Y, Heo H, Nguyen DH, Ellisman MH, Weinreb RN, Ju WK. Park SW, et al. Among authors: nguyen dh. Invest Ophthalmol Vis Sci. 2011 Apr 27;52(5):2837-43. doi: 10.1167/iovs.09-5010. Print 2011 Apr. Invest Ophthalmol Vis Sci. 2011. PMID: 21372007 Free PMC article.

10

Protection by an oral disubstituted hydroxylamine derivative against loss of retinal ganglion cell differentiation following optic nerve crush.

Lindsey JD, Duong-Polk KX, Dai Y, Nguyen DH, Leung CK, Weinreb RN. Lindsey JD, et al. Among authors: nguyen dh. PLoS One. 2013 Aug 5;8(8):e65966. doi: 10.1371/journal.pone.0065966. Print 2013. PLoS One. 2013. PMID: 23940507 Free PMC article.

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