Brown G - Search Results

1

Carbon-11 labelling of the antitumour agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and determination of plasma metabolites in man.

Brady F, Luthra SK, Brown G, Osman S, Harte RJ, Denny WA, Baguley BC, Jones T, Price PM. Brady F, et al. Among authors: brown g. Appl Radiat Isot. 1997 Apr;48(4):487-92. doi: 10.1016/s0969-8043(96)00294-1. Appl Radiat Isot. 1997. PMID: 9106990 Clinical Trial.

2

Antitumor imidazotetrazines. 40. Radiosyntheses of [4-11C-carbonyl]- and [3-N-11C-methyl]-8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (temozolomide) for positron emission tomography (PET) studies.

Brown GD, Luthra SK, Brock CS, Stevens MF, Price PM, Brady F. Brown GD, et al. J Med Chem. 2002 Dec 5;45(25):5448-57. doi: 10.1021/jm020921f. J Med Chem. 2002. PMID: 12459013

3

Pharmacokinetic evaluation of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in patients by positron emission tomography.

Saleem A, Harte RJ, Matthews JC, Osman S, Brady F, Luthra SK, Brown GD, Bleehen N, Connors T, Jones T, Price PM, Aboagye EO. Saleem A, et al. Among authors: brown gd. J Clin Oncol. 2001 Mar 1;19(5):1421-9. doi: 10.1200/JCO.2001.19.5.1421. J Clin Oncol. 2001. PMID: 11230487 Clinical Trial.

4

Comparative biodistribution and metabolism of carbon-11-labeled N-[2-(dimethylamino)ethyl]acridine-4-carboxamide and DNA-intercalating analogues.

Osman S, Rowlinson-Busza G, Luthra SK, Aboagye EO, Brown GD, Brady F, Myers R, Gamage SA, Denny WA, Baguley BC, Price PM. Osman S, et al. Among authors: brown gd. Cancer Res. 2001 Apr 1;61(7):2935-44. Cancer Res. 2001. PMID: 11306471

5

Two routes to [11C-carbonyl]organo-isocyanates utilizing [11C]phosgene ([11C]organo-isocyanates from [11C]phosgene).

Brown GD, Henderson D, Steel C, Luthra S, Price PM, Brady F. Brown GD, et al. Nucl Med Biol. 2001 Nov;28(8):991-8. doi: 10.1016/s0969-8051(01)00263-3. Nucl Med Biol. 2001. PMID: 11711319

6

Studies on the metabolism of the novel antitumor agent [N-methyl-11C]N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in rats and humans prior to phase I clinical trials.

Osman S, Luthra SK, Brady F, Hume SP, Brown G, Harte RJ, Matthews JC, Denny WA, Baguley BC, Jones T, Price PM. Osman S, et al. Among authors: brown g. Cancer Res. 1997 Jun 1;57(11):2172-80. Cancer Res. 1997. PMID: 9187117 Clinical Trial.

7

An automated radiosynthesis of 2-[11C]thymidine using anhydrous [11C]urea derived from [11C]phosgene.

Steel CJ, Brady F, Luthra SK, Brown G, Khan I, Poole KG, Sergis A, Jones T, Price PM. Steel CJ, et al. Among authors: brown g. Appl Radiat Isot. 1999 Oct;51(4):377-88. doi: 10.1016/s0969-8043(99)00051-2. Appl Radiat Isot. 1999. PMID: 10464914

8

Metabolic activation of temozolomide measured in vivo using positron emission tomography.

Saleem A, Brown GD, Brady F, Aboagye EO, Osman S, Luthra SK, Ranicar AS, Brock CS, Stevens MF, Newlands E, Jones T, Price P. Saleem A, et al. Among authors: brown gd. Cancer Res. 2003 May 15;63(10):2409-15. Cancer Res. 2003. PMID: 12750260

9

Radiolabelled tracers and anticancer drugs for assessment of therapeutic efficacy using PET.

Brady F, Luthra SK, Brown GD, Osman S, Aboagye E, Saleem A, Price PM. Brady F, et al. Among authors: brown gd. Curr Pharm Des. 2001 Dec;7(18):1863-92. doi: 10.2174/1381612013396907. Curr Pharm Des. 2001. PMID: 11772355 Review.

10

Positron emission tomography for tumour assessment.

Jones T, Tilsley DW, Wilson CB, Lammertsma AA, Brown G, Brady F, Price PM. Jones T, et al. Among authors: brown g. NMR Biomed. 1992 Sep-Oct;5(5):265-9. doi: 10.1002/nbm.1940050512. NMR Biomed. 1992. PMID: 1449966 Review.

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