Karn J - Search Results

1

An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication.

Hamy F, Felder ER, Heizmann G, Lazdins J, Aboul-ela F, Varani G, Karn J, Klimkait T. Hamy F, et al. Among authors: karn j. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3548-53. doi: 10.1073/pnas.94.8.3548. Proc Natl Acad Sci U S A. 1997. PMID: 9108013 Free PMC article.

2

Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro.

Dingwall C, Ernberg I, Gait MJ, Green SM, Heaphy S, Karn J, Lowe AD, Singh M, Skinner MA, Valerio R. Dingwall C, et al. Among authors: karn j. Proc Natl Acad Sci U S A. 1989 Sep;86(18):6925-9. doi: 10.1073/pnas.86.18.6925. Proc Natl Acad Sci U S A. 1989. PMID: 2476805 Free PMC article.

3

HIV gene regulatory proteins tat and rev and their interactions with synthetic RNA.

Asseline U, Grasby J, Hamy F, Iwai S, Mann DA, Pritchard C, Karn J, Gait MJ. Asseline U, et al. Among authors: karn j. Nucleic Acids Symp Ser. 1993;(29):113-4. Nucleic Acids Symp Ser. 1993. PMID: 7504239

4

The structure of the human immunodeficiency virus type-1 TAR RNA reveals principles of RNA recognition by Tat protein.

Aboul-ela F, Karn J, Varani G. Aboul-ela F, et al. Among authors: karn j. J Mol Biol. 1995 Oct 20;253(2):313-32. doi: 10.1006/jmbi.1995.0555. J Mol Biol. 1995. PMID: 7563092

5

The RNA element encoded by the trans-activation-responsive region of human immunodeficiency virus type 1 is functional when displaced downstream of the start of transcription.

Churcher MJ, Lowe AD, Gait MJ, Karn J. Churcher MJ, et al. Among authors: karn j. Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):2408-12. doi: 10.1073/pnas.92.6.2408. Proc Natl Acad Sci U S A. 1995. PMID: 7892280 Free PMC article.

6

Methylphosphonate mapping of phosphate contacts critical for RNA recognition by the human immunodeficiency virus tat and rev proteins.

Pritchard CE, Grasby JA, Hamy F, Zacharek AM, Singh M, Karn J, Gait MJ. Pritchard CE, et al. Among authors: karn j. Nucleic Acids Res. 1994 Jul 11;22(13):2592-600. doi: 10.1093/nar/22.13.2592. Nucleic Acids Res. 1994. PMID: 8041622 Free PMC article.

7

Human immunodeficiency virus type 1 transactivator protein, tat, stimulates transcriptional read-through of distal terminator sequences in vitro.

Graeble MA, Churcher MJ, Lowe AD, Gait MJ, Karn J. Graeble MA, et al. Among authors: karn j. Proc Natl Acad Sci U S A. 1993 Jul 1;90(13):6184-8. doi: 10.1073/pnas.90.13.6184. Proc Natl Acad Sci U S A. 1993. PMID: 8327498 Free PMC article.

8

Hydrogen-bonding contacts in the major groove are required for human immunodeficiency virus type-1 tat protein recognition of TAR RNA.

Hamy F, Asseline U, Grasby J, Iwai S, Pritchard C, Slim G, Butler PJ, Karn J, Gait MJ. Hamy F, et al. Among authors: karn j. J Mol Biol. 1993 Mar 5;230(1):111-23. doi: 10.1006/jmbi.1993.1129. J Mol Biol. 1993. PMID: 8450529

9

High affinity binding of TAR RNA by the human immunodeficiency virus type-1 tat protein requires base-pairs in the RNA stem and amino acid residues flanking the basic region.

Churcher MJ, Lamont C, Hamy F, Dingwall C, Green SM, Lowe AD, Butler JG, Gait MJ, Karn J. Churcher MJ, et al. Among authors: karn j. J Mol Biol. 1993 Mar 5;230(1):90-110. doi: 10.1006/jmbi.1993.1128. J Mol Biol. 1993. PMID: 8450553

10

Human immunodeficiency virus type-1 Tat is an integral component of the activated transcription-elongation complex.

Keen NJ, Gait MJ, Karn J. Keen NJ, et al. Among authors: karn j. Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2505-10. doi: 10.1073/pnas.93.6.2505. Proc Natl Acad Sci U S A. 1996. PMID: 8637904 Free PMC article.

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