Derynck R - Search Results

1

Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition.

Wang XJ, Greenhalgh DA, Bickenbach JR, Jiang A, Bundman DS, Krieg T, Derynck R, Roop DR. Wang XJ, et al. Among authors: derynck r. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2386-91. doi: 10.1073/pnas.94.6.2386. Proc Natl Acad Sci U S A. 1997. PMID: 9122204 Free PMC article.

2

Dominant-negative interference of the transforming growth factor beta type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice.

Gorska AE, Joseph H, Derynck R, Moses HL, Serra R. Gorska AE, et al. Among authors: derynck r. Cell Growth Differ. 1998 Mar;9(3):229-38. Cell Growth Differ. 1998. PMID: 9543389

3

Vgr-1, a mammalian gene related to Xenopus Vg-1, is a member of the transforming growth factor beta gene superfamily.

Lyons K, Graycar JL, Lee A, Hashmi S, Lindquist PB, Chen EY, Hogan BL, Derynck R. Lyons K, et al. Among authors: derynck r. Proc Natl Acad Sci U S A. 1989 Jun;86(12):4554-8. doi: 10.1073/pnas.86.12.4554. Proc Natl Acad Sci U S A. 1989. PMID: 2734307 Free PMC article.

4

TGF-beta regulates the mechanical properties and composition of bone matrix.

Balooch G, Balooch M, Nalla RK, Schilling S, Filvaroff EH, Marshall GW, Marshall SJ, Ritchie RO, Derynck R, Alliston T. Balooch G, et al. Among authors: derynck r. Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):18813-8. doi: 10.1073/pnas.0507417102. Epub 2005 Dec 14. Proc Natl Acad Sci U S A. 2005. PMID: 16354837 Free PMC article.

5

Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis.

Serra R, Johnson M, Filvaroff EH, LaBorde J, Sheehan DM, Derynck R, Moses HL. Serra R, et al. Among authors: derynck r. J Cell Biol. 1997 Oct 20;139(2):541-52. doi: 10.1083/jcb.139.2.541. J Cell Biol. 1997. PMID: 9334355 Free PMC article.

6

The type I TGF-beta receptor is covalently modified and regulated by sumoylation.

Kang JS, Saunier EF, Akhurst RJ, Derynck R. Kang JS, et al. Among authors: derynck r. Nat Cell Biol. 2008 Jun;10(6):654-64. doi: 10.1038/ncb1728. Epub 2008 May 11. Nat Cell Biol. 2008. PMID: 18469808 Free PMC article.

7

Increased transforming growth factor beta expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of Meth A sarcoma cells.

Chang HL, Gillett N, Figari I, Lopez AR, Palladino MA, Derynck R. Chang HL, et al. Among authors: derynck r. Cancer Res. 1993 Sep 15;53(18):4391-8. Cancer Res. 1993. PMID: 8364935

8

The type II transforming growth factor (TGF)-beta receptor-interacting protein TRIP-1 acts as a modulator of the TGF-beta response.

Choy L, Derynck R. Choy L, et al. Among authors: derynck r. J Biol Chem. 1998 Nov 20;273(47):31455-62. doi: 10.1074/jbc.273.47.31455. J Biol Chem. 1998. PMID: 9813058 Free article.

9

Complex regulation of transforming growth factor beta 1, beta 2, and beta 3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors beta 1 and beta 2.

Bascom CC, Wolfshohl JR, Coffey RJ Jr, Madisen L, Webb NR, Purchio AR, Derynck R, Moses HL. Bascom CC, et al. Among authors: derynck r. Mol Cell Biol. 1989 Dec;9(12):5508-15. doi: 10.1128/mcb.9.12.5508-5515.1989. Mol Cell Biol. 1989. PMID: 2586525 Free PMC article.

10

Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta -induced growth inhibition and apoptosis.

Patil S, Wildey GM, Brown TL, Choy L, Derynck R, Howe PH. Patil S, et al. Among authors: derynck r. J Biol Chem. 2000 Dec 8;275(49):38363-70. doi: 10.1074/jbc.M004861200. J Biol Chem. 2000. PMID: 10995749 Free article.

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