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Red wine polyphenolic compounds inhibit vascular endothelial growth factor expression in vascular smooth muscle cells by preventing the activation of the p38 mitogen-activated protein kinase pathway.
Oak MH, Chataigneau M, Keravis T, Chataigneau T, Beretz A, Andriantsitohaina R, Stoclet JC, Chang SJ, Schini-Kerth VB. Oak MH, et al. Among authors: beretz a. Arterioscler Thromb Vasc Biol. 2003 Jun 1;23(6):1001-7. doi: 10.1161/01.ATV.0000070101.70534.38. Epub 2003 Apr 3. Arterioscler Thromb Vasc Biol. 2003. PMID: 12676803
Tissue and substrate specificity of inhibition by alkoxy-aryl-lactams of platelet and arterial smooth muscle cyclic nucleotide phosphodiesterases relationship to pharmacological activity.
Lugnier C, Stierlé A, Beretz A, Schoeffter P, Lebec A, Wermuth CG, Cazenave JP, Stoclet JC. Lugnier C, et al. Among authors: beretz a. Biochem Biophys Res Commun. 1983 Jun 29;113(3):954-9. doi: 10.1016/0006-291x(83)91091-4. Biochem Biophys Res Commun. 1983. PMID: 6307307
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