Mapelli C - Search Results

1

Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.

Wittekind M, Mapelli C, Lee V, Goldfarb V, Friedrichs MS, Meyers CA, Mueller L. Wittekind M, et al. Among authors: mapelli c. J Mol Biol. 1997 Apr 11;267(4):933-52. doi: 10.1006/jmbi.1996.0886. J Mol Biol. 1997. PMID: 9135122

2

Orientation of peptide fragments from Sos proteins bound to the N-terminal SH3 domain of Grb2 determined by NMR spectroscopy.

Wittekind M, Mapelli C, Farmer BT 2nd, Suen KL, Goldfarb V, Tsao J, Lavoie T, Barbacid M, Meyers CA, Mueller L. Wittekind M, et al. Among authors: mapelli c. Biochemistry. 1994 Nov 22;33(46):13531-9. doi: 10.1021/bi00250a004. Biochemistry. 1994. PMID: 7947763

3

Micelle-bound conformational preferences of a peptide derived from a murine major histocompatibility complex class I molecule.

Constantine KL, Mapelli C, Meyers CA, Friedrichs MS, Krystek S, Mueller L. Constantine KL, et al. Among authors: mapelli c. J Biol Chem. 1993 Oct 25;268(30):22830-7. J Biol Chem. 1993. PMID: 8226794 Free article.

A., Bjorkmann, P. J., Strominger, T. L., and Wiley, D. C. (1989) Nature 342, 692-696). Structural features that are important for the bioactivity of [Ala85]Dk(69-85) are discussed with reference to reported structure-activity relationships (Stagsted, J., Mapelli, …

A., Bjorkmann, P. J., Strominger, T. L., and Wiley, D. C. (1989) Nature 342, 692-696). Structural features that are important for the …

4

Amino acid residues essential for biological activity of a peptide derived from a major histocompatibility complex class I antigen.

Stagsted J, Mapelli C, Meyers C, Matthews BW, Anfinsen CB, Goldstein A, Olsson L. Stagsted J, et al. Among authors: mapelli c. Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7686-90. doi: 10.1073/pnas.90.16.7686. Proc Natl Acad Sci U S A. 1993. PMID: 8356070 Free PMC article.

5

An inhibitor binding pocket distinct from the catalytic active site on human beta-APP cleaving enzyme.

Kornacker MG, Lai Z, Witmer M, Ma J, Hendrick J, Lee VG, Riexinger DJ, Mapelli C, Metzler W, Copeland RA. Kornacker MG, et al. Among authors: mapelli c. Biochemistry. 2005 Aug 30;44(34):11567-73. doi: 10.1021/bi050932l. Biochemistry. 2005. PMID: 16114893

6

Eleven amino acid glucagon-like peptide-1 receptor agonists with antidiabetic activity.

Mapelli C, Natarajan SI, Meyer JP, Bastos MM, Bernatowicz MS, Lee VG, Pluscec J, Riexinger DJ, Sieber-McMaster ES, Constantine KL, Smith-Monroy CA, Golla R, Ma Z, Longhi DA, Shi D, Xin L, Taylor JR, Koplowitz B, Chi CL, Khanna A, Robinson GW, Seethala R, Antal-Zimanyi IA, Stoffel RH, Han S, Whaley JM, Huang CS, Krupinski J, Ewing WR. Mapelli C, et al. J Med Chem. 2009 Dec 10;52(23):7788-99. doi: 10.1021/jm900752a. J Med Chem. 2009. PMID: 19702274

7

Identification of potent 11mer glucagon-like peptide-1 receptor agonist peptides with novel C-terminal amino acids: Homohomophenylalanine analogs.

Haque TS, Lee VG, Riexinger D, Lei M, Malmstrom S, Xin L, Han S, Mapelli C, Cooper CB, Zhang G, Ewing WR, Krupinski J. Haque TS, et al. Among authors: mapelli c. Peptides. 2010 May;31(5):950-5. doi: 10.1016/j.peptides.2010.01.008. Epub 2010 Feb 4. Peptides. 2010. PMID: 20138099

8

Exploration of structure-activity relationships at the two C-terminal residues of potent 11mer Glucagon-Like Peptide-1 receptor agonist peptides via parallel synthesis.

Haque TS, Martinez RL, Lee VG, Riexinger DG, Lei M, Feng M, Koplowitz B, Mapelli C, Cooper CB, Zhang G, Huang C, Ewing WR, Krupinski J. Haque TS, et al. Among authors: mapelli c. Peptides. 2010 Jul;31(7):1353-60. doi: 10.1016/j.peptides.2010.04.013. Epub 2010 Apr 24. Peptides. 2010. PMID: 20420872

9

Synthesis of a stable isotopically labeled universal surrogate peptide for use as an internal standard in LC-MS/MS bioanalysis of human IgG and Fc-fusion protein drug candidates.

Voronin K, Allentoff AJ, Bonacorsi SJ Jr, Mapelli C, Gong SX, Lee V, Riexinger D, Sanghvi N, Jiang H, Zeng J. Voronin K, et al. Among authors: mapelli c. J Labelled Comp Radiopharm. 2014 Jul;57(9):579-83. doi: 10.1002/jlcr.3218. Epub 2014 Aug 4. J Labelled Comp Radiopharm. 2014. PMID: 25089024

10

Mcl-1 antagonism is a potential therapeutic strategy in a subset of solid cancers.

Modugno M, Banfi P, Gasparri F, Borzilleri R, Carter P, Cornelius L, Gottardis M, Lee V, Mapelli C, Naglich JG, Tebben A, Vite G, Pastori W, Albanese C, Corti E, Ballinari D, Galvani A. Modugno M, et al. Among authors: mapelli c. Exp Cell Res. 2015 Mar 15;332(2):267-77. doi: 10.1016/j.yexcr.2014.11.022. Epub 2014 Dec 5. Exp Cell Res. 2015. PMID: 25486070

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