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5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile.
Daluge SM, Purifoy DJ, Savina PM, St Clair MH, Parry NR, Dev IK, Novak P, Ayers KM, Reardon JE, Roberts GB, et al. Daluge SM, et al. Among authors: st clair mh. Antimicrob Agents Chemother. 1994 Jul;38(7):1590-603. doi: 10.1128/AAC.38.7.1590. Antimicrob Agents Chemother. 1994. PMID: 7526782 Free PMC article.
Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells.
Dornsife RE, St Clair MH, Huang AT, Panella TJ, Koszalka GW, Burns CL, Averett DR. Dornsife RE, et al. Among authors: st clair mh. Antimicrob Agents Chemother. 1991 Feb;35(2):322-8. doi: 10.1128/AAC.35.2.322. Antimicrob Agents Chemother. 1991. PMID: 1708977 Free PMC article.
Anti-human immunodeficiency virus type 1 activity of the nonnucleoside reverse transcriptase inhibitor GW678248 in combination with other antiretrovirals against clinical isolate viruses and in vitro selection for resistance.
Hazen RJ, Harvey RJ, St Clair MH, Ferris RG, Freeman GA, Tidwell JH, Schaller LT, Cowan JR, Short SA, Romines KR, Chan JH, Boone LR. Hazen RJ, et al. Among authors: st clair mh. Antimicrob Agents Chemother. 2005 Nov;49(11):4465-73. doi: 10.1128/AAC.49.11.4465-4473.2005. Antimicrob Agents Chemother. 2005. PMID: 16251284 Free PMC article.
In vitro antiviral activity of the novel, tyrosyl-based human immunodeficiency virus (HIV) type 1 protease inhibitor brecanavir (GW640385) in combination with other antiretrovirals and against a panel of protease inhibitor-resistant HIV.
Hazen R, Harvey R, Ferris R, Craig C, Yates P, Griffin P, Miller J, Kaldor I, Ray J, Samano V, Furfine E, Spaltenstein A, Hale M, Tung R, St Clair M, Hanlon M, Boone L. Hazen R, et al. Antimicrob Agents Chemother. 2007 Sep;51(9):3147-54. doi: 10.1128/AAC.00401-07. Epub 2007 Jul 9. Antimicrob Agents Chemother. 2007. PMID: 17620375 Free PMC article.
93 results