O'Connor B - Search Results

1

Intracellular location of thymidylate synthase and its state of phosphorylation.

Samsonoff WA, Reston J, McKee M, O'Connor B, Galivan J, Maley G, Maley F. Samsonoff WA, et al. J Biol Chem. 1997 May 16;272(20):13281-5. doi: 10.1074/jbc.272.20.13281. J Biol Chem. 1997. PMID: 9148948 Free article.

2

Biological activity of a novel rationally designed lipophilic thymidylate synthase inhibitor.

O'Connor BM, Webber S, Jackson RC, Galivan J, Rhee MS. O'Connor BM, et al. Cancer Chemother Pharmacol. 1994;34(3):225-9. doi: 10.1007/BF00685081. Cancer Chemother Pharmacol. 1994. PMID: 8004755

3

Secretion of gamma-glutamyl hydrolase in vitro.

O'Connor BM, Rotundo RF, Nimec Z, McGuire JJ, Galivan J. O'Connor BM, et al. Cancer Res. 1991 Aug 1;51(15):3874-81. Cancer Res. 1991. PMID: 1713122

4

The properties and function of gamma-glutamyl hydrolase and poly-gamma-glutamate.

Wang Y, Dias JA, Nimec Z, Rotundo R, O'Connor BM, Freisheim J, Galivan J. Wang Y, et al. Adv Enzyme Regul. 1993;33:207-18. doi: 10.1016/0065-2571(93)90019-a. Adv Enzyme Regul. 1993. PMID: 7689289

5

Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.

Rosowsky A, Galivan J, Beardsley GP, Bader H, O'Connor BM, Russello O, Moroson BA, DeYarman MT, Kerwar SS, Freisheim JH. Rosowsky A, et al. Cancer Res. 1992 Apr 15;52(8):2148-55. Cancer Res. 1992. PMID: 1313737

6

Quinazoline antifolate thymidylate synthase inhibitors: heterocyclic benzoyl ring modifications.

Marsham PR, Hughes LR, Jackman AL, Hayter AJ, Oldfield J, Wardleworth JM, Bishop JA, O'Connor BM, Calvert AH. Marsham PR, et al. J Med Chem. 1991 May;34(5):1594-605. doi: 10.1021/jm00109a011. J Med Chem. 1991. PMID: 2033585

7

Quinoline antifolate thymidylate synthase inhibitors: variation of the C2- and C4-substituents.

Warner P, Barker AJ, Jackman AL, Burrows KD, Roberts N, Bishop JA, O'Connor BM, Hughes LR. Warner P, et al. J Med Chem. 1992 Jul 24;35(15):2761-8. doi: 10.1021/jm00093a007. J Med Chem. 1992. PMID: 1495009

8

Identification of the major phosphorylation domain of murine mdr1b P-glycoprotein. Analysis of the protein kinase A and protein kinase C phosphorylation sites.

Orr GA, Han EK, Browne PC, Nieves E, O'Connor BM, Yang CP, Horwitz SB. Orr GA, et al. J Biol Chem. 1993 Nov 25;268(33):25054-62. J Biol Chem. 1993. PMID: 7901220 Free article.

9

Quinazoline antifolate thymidylate synthase inhibitors: replacement of glutamic acid in the C2-methyl series.

Marsham PR, Jackman AL, Barker AJ, Boyle FT, Pegg SJ, Wardleworth JM, Kimbell R, O'Connor BM, Calvert AH, Hughes LR. Marsham PR, et al. J Med Chem. 1995 Mar 17;38(6):994-1004. doi: 10.1021/jm00006a019. J Med Chem. 1995. PMID: 7699716

10

Quinazoline antifolates inhibiting thymidylate synthase: 4-thio-substituted analogues.

Thornton TJ, Jones TR, Jackman AL, Flinn A, O'Connor BM, Warner P, Calvert AH. Thornton TJ, et al. J Med Chem. 1991 Mar;34(3):978-84. doi: 10.1021/jm00107a015. J Med Chem. 1991. PMID: 2002476

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