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The CoREST complex inhibitor, corin, leads to decreased tumor growth, increased cellular differentiation and extended lifespan in atypical teratoid rhabdoid tumor xenograft models.
Geethadevi A, Vaidya N, Fisher RJ, Findlay T, Deng Y, Pham K, Kumar V, Beck S, Lucas CG, Eberhart CG, Xu J, Cole PA, Rubens J, Collard M, Raabe EH, Alani RM. Geethadevi A, et al. Among authors: cole pa. bioRxiv [Preprint]. 2024 Dec 17:2024.12.14.628381. doi: 10.1101/2024.12.14.628381. bioRxiv. 2024. PMID: 39763800 Free PMC article. Preprint.
Transplant-Free Approach in Relapsed Hodgkin Lymphoma in Children, Adolescents, and Young Adults: A Nonrandomized Clinical Trial.
Daw S, Cole PD, Hoppe BS, Hodgson D, Beishuizen A, Garnier N, Buffardi S, Mascarin M, Lissat A, Mauz-Körholz C, Krajewski J, Akyol A, Crowe R, Anderson B, Xu Y, Drachtman RA, Kelly KM, Leblanc T, Harker-Murray P. Daw S, et al. Among authors: cole pd. JAMA Oncol. 2025 Jan 2. doi: 10.1001/jamaoncol.2024.5627. Online ahead of print. JAMA Oncol. 2025. PMID: 39745739
CoREST Complex Inhibition Alters RNA Splicing to Promote Neoantigen Expression and Enhance Tumor Immunity.
Fisher RJ, Park K, Lee K, Pinjusic K, Vanasse A, Ennis CS, Ficcaro S, Marto J, Stransky S, Duke-Cohan J, Geethadevi A, Raabe E, Sidoli S, Hicks CW, Keskin DB, Wu CJ, Cole PA, Alani RM. Fisher RJ, et al. Among authors: cole pa. bioRxiv [Preprint]. 2024 Dec 12:2024.12.12.627852. doi: 10.1101/2024.12.12.627852. bioRxiv. 2024. PMID: 39713349 Free PMC article. Preprint.
1,925 results