Lepock JR - Search Results

1

Function of the Greek key connection analysed using circular permutants of superoxide dismutase.

Boissinot M, Karnas S, Lepock JR, Cabelli DE, Tainer JA, Getzoff ED, Hallewell RA. Boissinot M, et al. Among authors: lepock jr. EMBO J. 1997 May 1;16(9):2171-8. doi: 10.1093/emboj/16.9.2171. EMBO J. 1997. PMID: 9171332 Free PMC article.

2

Changes in crystallographic structure and thermostability of a Cu,Zn superoxide dismutase mutant resulting from the removal of a buried cysteine.

McRee DE, Redford SM, Getzoff ED, Lepock JR, Hallewell RA, Tainer JA. McRee DE, et al. Among authors: lepock jr. J Biol Chem. 1990 Aug 25;265(24):14234-41. doi: 10.2210/pdb3sod/pdb. J Biol Chem. 1990. PMID: 2387847 Free article.

3

Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface.

Borgstahl GE, Parge HE, Hickey MJ, Johnson MJ, Boissinot M, Hallewell RA, Lepock JR, Cabelli DE, Tainer JA. Borgstahl GE, et al. Among authors: lepock jr. Biochemistry. 1996 Apr 9;35(14):4287-97. doi: 10.1021/bi951892w. Biochemistry. 1996. PMID: 8605177

4

Novel dimeric interface and electrostatic recognition in bacterial Cu,Zn superoxide dismutase.

Bourne Y, Redford SM, Steinman HM, Lepock JR, Tainer JA, Getzoff ED. Bourne Y, et al. Among authors: lepock jr. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):12774-9. doi: 10.1073/pnas.93.23.12774. Proc Natl Acad Sci U S A. 1996. PMID: 8917495 Free PMC article.

5

Crystal structure of Y34F mutant human mitochondrial manganese superoxide dismutase and the functional role of tyrosine 34.

Guan Y, Hickey MJ, Borgstahl GE, Hallewell RA, Lepock JR, O'Connor D, Hsieh Y, Nick HS, Silverman DN, Tainer JA. Guan Y, et al. Among authors: lepock jr. Biochemistry. 1998 Apr 7;37(14):4722-30. doi: 10.1021/bi972394l. Biochemistry. 1998. PMID: 9537987

6

Contribution of conformational stability and reversibility of unfolding to the increased thermostability of human and bovine superoxide dismutase mutated at free cysteines.

Lepock JR, Frey HE, Hallewell RA. Lepock JR, et al. J Biol Chem. 1990 Dec 15;265(35):21612-8. J Biol Chem. 1990. PMID: 2254318 Free article.

7

Multiple replacements of glutamine 143 in human manganese superoxide dismutase: effects on structure, stability, and catalysis.

Lévêque VJ, Stroupe ME, Lepock JR, Cabelli DE, Tainer JA, Nick HS, Silverman DN. Lévêque VJ, et al. Among authors: lepock jr. Biochemistry. 2000 Jun 20;39(24):7131-7. doi: 10.1021/bi9929958. Biochemistry. 2000. PMID: 10852710

8

Amino acid substitution at the dimeric interface of human manganese superoxide dismutase.

Hearn AS, Fan L, Lepock JR, Luba JP, Greenleaf WB, Cabelli DE, Tainer JA, Nick HS, Silverman DN. Hearn AS, et al. Among authors: lepock jr. J Biol Chem. 2004 Feb 13;279(7):5861-6. doi: 10.1074/jbc.M311310200. Epub 2003 Nov 24. J Biol Chem. 2004. PMID: 14638684 Free article.

9

Role of hydrogen bonding in the active site of human manganese superoxide dismutase.

Greenleaf WB, Perry JJ, Hearn AS, Cabelli DE, Lepock JR, Stroupe ME, Tainer JA, Nick HS, Silverman DN. Greenleaf WB, et al. Among authors: lepock jr. Biochemistry. 2004 Jun 8;43(22):7038-45. doi: 10.1021/bi049888k. Biochemistry. 2004. PMID: 15170341

10

Kinetic analysis of product inhibition in human manganese superoxide dismutase.

Hearn AS, Stroupe ME, Cabelli DE, Lepock JR, Tainer JA, Nick HS, Silverman DN. Hearn AS, et al. Among authors: lepock jr. Biochemistry. 2001 Oct 9;40(40):12051-8. doi: 10.1021/bi011047f. Biochemistry. 2001. PMID: 11580280

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