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Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue.
Podlisny MB, Citron M, Amarante P, Sherrington R, Xia W, Zhang J, Diehl T, Levesque G, Fraser P, Haass C, Koo EH, Seubert P, St George-Hyslop P, Teplow DB, Selkoe DJ. Podlisny MB, et al. Among authors: koo eh. Neurobiol Dis. 1997;3(4):325-37. doi: 10.1006/nbdi.1997.0129. Neurobiol Dis. 1997. PMID: 9173929
237 results