Piper PW - Search Results

1

A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone.

Prodromou C, Roe SM, Piper PW, Pearl LH. Prodromou C, et al. Among authors: piper pw. Nat Struct Biol. 1997 Jun;4(6):477-82. doi: 10.1038/nsb0697-477. Nat Struct Biol. 1997. PMID: 9187656

2

Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast.

Piper PW, Millson SH, Mollapour M, Panaretou B, Siligardi G, Pearl LH, Prodromou C. Piper PW, et al. Eur J Biochem. 2003 Dec;270(23):4689-95. doi: 10.1046/j.1432-1033.2003.03866.x. Eur J Biochem. 2003. PMID: 14622256 Free article.

3

The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37).

Roe SM, Ali MM, Meyer P, Vaughan CK, Panaretou B, Piper PW, Prodromou C, Pearl LH. Roe SM, et al. Among authors: piper pw. Cell. 2004 Jan 9;116(1):87-98. doi: 10.1016/s0092-8674(03)01027-4. Cell. 2004. PMID: 14718169 Free article.

4

Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery.

Meyer P, Prodromou C, Liao C, Hu B, Mark Roe S, Vaughan CK, Vlasic I, Panaretou B, Piper PW, Pearl LH. Meyer P, et al. Among authors: piper pw. EMBO J. 2004 Feb 11;23(3):511-9. doi: 10.1038/sj.emboj.7600060. Epub 2004 Jan 22. EMBO J. 2004. Corrected and republished in: EMBO J. 2004 Mar 24;23(6):1402-10. doi: 10.1038/sj.emboj.7600141 PMID: 14739935 Free PMC article. Corrected and republished.

5

Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery.

Meyer P, Prodromou C, Liao C, Hu B, Roe SM, Vaughan CK, Vlasic I, Panaretou B, Piper PW, Pearl LH. Meyer P, et al. Among authors: piper pw. EMBO J. 2004 Mar 24;23(6):1402-10. doi: 10.1038/sj.emboj.7600141. EMBO J. 2004. PMID: 15039704 Free PMC article.

6

Investigating the protein-protein interactions of the yeast Hsp90 chaperone system by two-hybrid analysis: potential uses and limitations of this approach.

Millson SH, Truman AW, Wolfram F, King V, Panaretou B, Prodromou C, Pearl LH, Piper PW. Millson SH, et al. Among authors: piper pw. Cell Stress Chaperones. 2004 Winter;9(4):359-68. doi: 10.1379/csc-29r1.1. Cell Stress Chaperones. 2004. PMID: 15633294 Free PMC article.

7

A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein kinase, Slt2p (Mpk1p).

Millson SH, Truman AW, King V, Prodromou C, Pearl LH, Piper PW. Millson SH, et al. Among authors: piper pw. Eukaryot Cell. 2005 May;4(5):849-60. doi: 10.1128/EC.4.5.849-860.2005. Eukaryot Cell. 2005. PMID: 15879519 Free PMC article.

8

Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex.

Ali MM, Roe SM, Vaughan CK, Meyer P, Panaretou B, Piper PW, Prodromou C, Pearl LH. Ali MM, et al. Among authors: piper pw. Nature. 2006 Apr 20;440(7087):1013-7. doi: 10.1038/nature04716. Nature. 2006. PMID: 16625188 Free PMC article.

9

Chaperone ligand-discrimination by the TPR-domain protein Tah1.

Millson SH, Vaughan CK, Zhai C, Ali MM, Panaretou B, Piper PW, Pearl LH, Prodromou C. Millson SH, et al. Among authors: piper pw. Biochem J. 2008 Jul 15;413(2):261-8. doi: 10.1042/BJ20080105. Biochem J. 2008. PMID: 18412542 Free PMC article.

10

A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s.

Vaughan CK, Piper PW, Pearl LH, Prodromou C. Vaughan CK, et al. Among authors: piper pw. FEBS J. 2009 Jan;276(1):199-209. doi: 10.1111/j.1742-4658.2008.06773.x. Epub 2008 Nov 20. FEBS J. 2009. PMID: 19032597 Free PMC article.

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