Murcko MA - Search Results

1

Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication.

Xu J, Mendez E, Caron PR, Lin C, Murcko MA, Collett MS, Rice CM. Xu J, et al. Among authors: murcko ma. J Virol. 1997 Jul;71(7):5312-22. doi: 10.1128/JVI.71.7.5312-5322.1997. J Virol. 1997. PMID: 9188600 Free PMC article.

2

Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide.

Kim JL, Morgenstern KA, Lin C, Fox T, Dwyer MD, Landro JA, Chambers SP, Markland W, Lepre CA, O'Malley ET, Harbeson SL, Rice CM, Murcko MA, Caron PR, Thomson JA. Kim JL, et al. Among authors: murcko ma. Cell. 1996 Oct 18;87(2):343-55. doi: 10.1016/s0092-8674(00)81351-3. Cell. 1996. PMID: 8861917 Free article.

3

Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding.

Kim JL, Morgenstern KA, Griffith JP, Dwyer MD, Thomson JA, Murcko MA, Lin C, Caron PR. Kim JL, et al. Among authors: murcko ma. Structure. 1998 Jan 15;6(1):89-100. doi: 10.1016/s0969-2126(98)00010-0. Structure. 1998. PMID: 9493270 Free article.

4

Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid.

Sintchak MD, Fleming MA, Futer O, Raybuck SA, Chambers SP, Caron PR, Murcko MA, Wilson KP. Sintchak MD, et al. Among authors: murcko ma. Cell. 1996 Jun 14;85(6):921-30. doi: 10.1016/s0092-8674(00)81275-1. Cell. 1996. PMID: 8681386 Free article.

5

Transforming the genome to drug discovery.

Murcko M, Caron P. Murcko M, et al. Drug Discov Today. 2002 Jun 1;7(11):583-4. doi: 10.1016/s1359-6446(02)02267-5. Drug Discov Today. 2002. PMID: 12047860 No abstract available.

6

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase.

Wilson KP, McCaffrey PG, Hsiao K, Pazhanisamy S, Galullo V, Bemis GW, Fitzgibbon MJ, Caron PR, Murcko MA, Su MS. Wilson KP, et al. Among authors: murcko ma. Chem Biol. 1997 Jun;4(6):423-31. doi: 10.1016/s1074-5521(97)90194-0. Chem Biol. 1997. PMID: 9224565

7

Chemogenomic approaches to drug discovery.

Caron PR, Mullican MD, Mashal RD, Wilson KP, Su MS, Murcko MA. Caron PR, et al. Among authors: murcko ma. Curr Opin Chem Biol. 2001 Aug;5(4):464-70. doi: 10.1016/s1367-5931(00)00229-5. Curr Opin Chem Biol. 2001. PMID: 11470611 Review. No abstract available.

8

Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics.

Perni RB, Chandorkar G, Cottrell KM, Gates CA, Lin C, Lin K, Luong YP, Maxwell JP, Murcko MA, Pitlik J, Rao G, Schairer WC, Van Drie J, Wei Y. Perni RB, et al. Among authors: murcko ma. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3406-11. doi: 10.1016/j.bmcl.2007.03.090. Epub 2007 Apr 3. Bioorg Med Chem Lett. 2007. PMID: 17482818

9

Inhibitors of hepatitis C virus NS3.4A protease. Part 3: P2 proline variants.

Perni RB, Farmer LJ, Cottrell KM, Court JJ, Courtney LF, Deininger DD, Gates CA, Harbeson SL, Kim JL, Lin C, Lin K, Luong YP, Maxwell JP, Murcko MA, Pitlik J, Rao BG, Schairer WC, Tung RD, Van Drie JH, Wilson K, Thomson JA. Perni RB, et al. Among authors: murcko ma. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1939-42. doi: 10.1016/j.bmcl.2004.01.078. Bioorg Med Chem Lett. 2004. PMID: 15050632

10

Charged surface residues of FKBP12 participate in formation of the FKBP12-FK506-calcineurin complex.

Aldape RA, Futer O, DeCenzo MT, Jarrett BP, Murcko MA, Livingston DJ. Aldape RA, et al. Among authors: murcko ma. J Biol Chem. 1992 Aug 15;267(23):16029-32. J Biol Chem. 1992. PMID: 1379588 Free article.

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