Schwalbe CH - Search Results

1

Structural studies on bioactive compounds. 28. Selective activity of triazenyl-substituted pyrimethamine derivatives against Pneumocystis carinii dihydrofolate reductase.

Stevens MF, Phillip KS, Rathbone DL, O'Shea DM, Queener SF, Schwalbe CH, Lambert PA. Stevens MF, et al. Among authors: schwalbe ch. J Med Chem. 1997 Jun 6;40(12):1886-93. doi: 10.1021/jm970050n. J Med Chem. 1997. PMID: 9191966

2

Structural studies on bio-active compounds. 20. Molecular modeling and crystallographic studies on methylbenzoprim, a potent inhibitor of dihydrofolate reductase.

Denny BJ, Ringan NS, Schwalbe CH, Lambert PA, Meek MA, Griffin RJ, Stevens MF. Denny BJ, et al. Among authors: schwalbe ch. J Med Chem. 1992 Jun 12;35(12):2315-20. doi: 10.1021/jm00090a023. J Med Chem. 1992. PMID: 1613754

3

Structural studies on tazobactam.

Toomer CA, Schwalbe CH, Ringan NS, Lambert PA, Lowe PR, Lee VJ. Toomer CA, et al. Among authors: schwalbe ch. J Med Chem. 1991 Jul;34(7):1944-7. doi: 10.1021/jm00111a003. J Med Chem. 1991. PMID: 1648618

4

Structural studies on bio-active compounds. Part XV. Structure-activity relationships for pyrimethamine and a series of diaminopyrimidine analogues versus bacterial dihydrofolate reductase.

Sansom CE, Schwalbe CH, Lambert PA, Griffin RJ, Stevens MF. Sansom CE, et al. Among authors: schwalbe ch. Biochim Biophys Acta. 1989 Mar 16;995(1):21-7. doi: 10.1016/0167-4838(89)90228-8. Biochim Biophys Acta. 1989. PMID: 2647153

5

Structural studies on bioactive compounds. 8. Synthesis, crystal structure, and biological properties of a new series of 2,4-diamino-5-aryl-6-ethylpyrimidine dihydrofolate reductase inhibitors with in vivo activity against a methotrexate-resistant tumor cell line.

Griffin RJ, Meek MA, Schwalbe CH, Stevens MF. Griffin RJ, et al. Among authors: schwalbe ch. J Med Chem. 1989 Nov;32(11):2468-74. doi: 10.1021/jm00131a009. J Med Chem. 1989. PMID: 2810335

6

Quinols as novel therapeutic agents. 2.(1) 4-(1-Arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents.

Berry JM, Bradshaw TD, Fichtner I, Ren R, Schwalbe CH, Wells G, Chew EH, Stevens MF, Westwell AD. Berry JM, et al. Among authors: schwalbe ch. J Med Chem. 2005 Jan 27;48(2):639-44. doi: 10.1021/jm040859h. J Med Chem. 2005. PMID: 15658878

7

Antitumor imidazotetrazines. 25. Crystal structure of 8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (temozolomide) and structural comparisons with the related drugs mitozolomide and DTIC.

Lowe PR, Sansom CE, Schwalbe CH, Stevens MF, Clark AS. Lowe PR, et al. Among authors: schwalbe ch. J Med Chem. 1992 Sep 4;35(18):3377-82. doi: 10.1021/jm00096a013. J Med Chem. 1992. PMID: 1527789

8

Structural studies on bio-active compounds. Part 9. 2,4-Diamino-6-azidoquinazoline hydrochloride.

Schwalbe CH, King ME, Wong KP, Lambert PA, Bliss A, Stevens MF. Schwalbe CH, et al. Anticancer Drug Des. 1987 Dec;2(3):289-96. Anticancer Drug Des. 1987. PMID: 3449092

9

Structural studies on bio-active compounds. Part XIV. Molecular modelling of the interactions between pentamidine and DNA.

Sansom CE, Laughton CA, Neidle S, Schwalbe CH, Stevens MF. Sansom CE, et al. Among authors: schwalbe ch. Anticancer Drug Des. 1990 Aug;5(3):243-8. Anticancer Drug Des. 1990. PMID: 2400537

10

Structural studies on bioactive compounds. Part 26. Hydrogen bonding in the crystal structure of the N-methylformamide solvate of the immunomodulatory agent 2-amino-5-bromo-6-phenylpyrimidin-4-one (bropirimine): implications for the design of novel anti-tumour strategies.

Stevens MF, Schwalbe CH, Patel N, Gate EN, Bryant PK. Stevens MF, et al. Among authors: schwalbe ch. Anticancer Drug Des. 1995 Apr;10(3):203-13. Anticancer Drug Des. 1995. PMID: 7748455

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

43 results

Search Page

Filters