Mutagenesis of cysteine residues in the human gonadotropin alpha subunit. Roles of individual disulfide bonds in secretion, assembly, and biologic activity.
Furuhashi M, Ando H, Bielinska M, Pixley MR, Shikone T, Hsueh AJ, Boime I.
Furuhashi M, et al. Among authors: boime i.
J Biol Chem. 1994 Oct 14;269(41):25543-8.
J Biol Chem. 1994.
PMID: 7929256
Free article.
This contrasts with observations of the hCG beta subunit where all the disulfide bonds are required for efficient combination and folding (Suganuma, N., Matzuk, M., and Boime, I. (1989) J. Biol. Chem. 264, 19302-19307). In addition, the lack of secretion of some mut …
This contrasts with observations of the hCG beta subunit where all the disulfide bonds are required for efficient combination and folding (S …