Francis JW - Search Results

1

Intrathecal administration of recombinant human superoxide dismutase 1 in amyotrophic lateral sclerosis: a preliminary safety and pharmacokinetic study.

Cudkowicz ME, Warren L, Francis JW, Lloyd KJ, Friedlander RM, Borges LF, Kassem N, Munsat TL, Brown RH Jr. Cudkowicz ME, et al. Among authors: francis jw. Neurology. 1997 Jul;49(1):213-22. doi: 10.1212/wnl.49.1.213. Neurology. 1997. PMID: 9222193 Clinical Trial.

2

Postischemic infusion of Cu/Zn superoxide dismutase or SOD:Tet451 reduces cerebral infarction following focal ischemia/reperfusion in rats.

Francis JW, Ren J, Warren L, Brown RH Jr, Finklestein SP. Francis JW, et al. Exp Neurol. 1997 Aug;146(2):435-43. doi: 10.1006/exnr.1997.6547. Exp Neurol. 1997. PMID: 9270054

3

Survival in transgenic ALS mice does not vary with CNS glutathione peroxidase activity.

Cudkowicz ME, Pastusza KA, Sapp PC, Mathews RK, Leahy J, Pasinelli P, Francis JW, Jiang D, Andersen JK, Brown RH Jr. Cudkowicz ME, et al. Among authors: francis jw. Neurology. 2002 Sep 10;59(5):729-34. doi: 10.1212/wnl.59.5.729. Neurology. 2002. PMID: 12221165

4

VEGF increases blood-brain barrier permeability to Evans blue dye and tetanus toxin fragment C but not adeno-associated virus in ALS mice.

Ay I, Francis JW, Brown RH Jr. Ay I, et al. Among authors: francis jw. Brain Res. 2008 Oct 9;1234:198-205. doi: 10.1016/j.brainres.2008.07.121. Epub 2008 Aug 12. Brain Res. 2008. PMID: 18725212

5

Tetanus toxin fragment C fusion facilitates protein delivery to CNS neurons from cerebrospinal fluid in mice.

Benn SC, Ay I, Bastia E, Chian RJ, Celia SA, Pepinsky RB, Fishman PS, Brown RH Jr, Francis JW. Benn SC, et al. Among authors: francis jw. J Neurochem. 2005 Nov;95(4):1118-31. doi: 10.1111/j.1471-4159.2005.03459.x. J Neurochem. 2005. PMID: 16271047 Free article.

6

IGF-1:tetanus toxin fragment C fusion protein improves delivery of IGF-1 to spinal cord but fails to prolong survival of ALS mice.

Chian RJ, Li J, Ay I, Celia SA, Kashi BB, Tamrazian E, Matthews JC, Bronson RT, Rossomando A, Pepinsky RB, Fishman PS, Brown RH Jr, Francis JW. Chian RJ, et al. Among authors: francis jw. Brain Res. 2009 Sep 1;1287:1-19. doi: 10.1016/j.brainres.2009.06.066. Epub 2009 Jun 27. Brain Res. 2009. PMID: 19563785

7

Insect GDNF:TTC fusion protein improves delivery of GDNF to mouse CNS.

Li J, Chian RJ, Ay I, Kashi BB, Celia SA, Tamrazian E, Pepinsky RB, Fishman PS, Brown RH Jr, Francis JW. Li J, et al. Among authors: francis jw. Biochem Biophys Res Commun. 2009 Dec 18;390(3):947-51. doi: 10.1016/j.bbrc.2009.10.083. Epub 2009 Oct 21. Biochem Biophys Res Commun. 2009. PMID: 19852934

8

Tetanus toxin fragment C as a vector to enhance delivery of proteins to the CNS.

Francis JW, Bastia E, Matthews CC, Parks DA, Schwarzschild MA, Brown RH Jr, Fishman PS. Francis JW, et al. Brain Res. 2004 Jun 11;1011(1):7-13. doi: 10.1016/j.brainres.2004.03.007. Brain Res. 2004. PMID: 15140640

9

Heterogeneity of subcellular localization and electrophoretic mobility of survival motor neuron (SMN) protein in mammalian neural cells and tissues.

Francis JW, Sandrock AW, Bhide PG, Vonsattel JP, Brown RH Jr. Francis JW, et al. Proc Natl Acad Sci U S A. 1998 May 26;95(11):6492-7. doi: 10.1073/pnas.95.11.6492. Proc Natl Acad Sci U S A. 1998. PMID: 9600994 Free PMC article.

10

CuZn superoxide dismutase (SOD-1):tetanus toxin fragment C hybrid protein for targeted delivery of SOD-1 to neuronal cells.

Francis JW, Hosler BA, Brown RH Jr, Fishman PS. Francis JW, et al. J Biol Chem. 1995 Jun 23;270(25):15434-42. doi: 10.1074/jbc.270.25.15434. J Biol Chem. 1995. PMID: 7797532 Free article.

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