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All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders.

Rowley JD, Reshmi S, Sobulo O, Musvee T, Anastasi J, Raimondi S, Schneider NR, Barredo JC, Cantu ES, Schlegelberger B, Behm F, Doggett NA, Borrow J, Zeleznik-Le N. Rowley JD, et al. Among authors: sobulo o. Blood. 1997 Jul 15;90(2):535-41. Blood. 1997. PMID: 9226152 Free article.

MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).

Sobulo OM, Borrow J, Tomek R, Reshmi S, Harden A, Schlegelberger B, Housman D, Doggett NA, Rowley JD, Zeleznik-Le NJ. Sobulo OM, et al. Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8732-7. doi: 10.1073/pnas.94.16.8732. Proc Natl Acad Sci U S A. 1997. PMID: 9238046 Free PMC article.

Identification of complex genomic breakpoint junctions in the t(9;11) MLL-AF9 fusion gene in acute leukemia.

Super HG, Strissel PL, Sobulo OM, Burian D, Reshmi SC, Roe B, Zeleznik-Le NJ, Diaz MO, Rowley JD. Super HG, et al. Among authors: sobulo om. Genes Chromosomes Cancer. 1997 Oct;20(2):185-95. Genes Chromosomes Cancer. 1997. PMID: 9331569

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