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Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes.
Nishina H, Bachmann M, Oliveira-dos-Santos AJ, Kozieradzki I, Fischer KD, Odermatt B, Wakeham A, Shahinian A, Takimoto H, Bernstein A, Mak TW, Woodgett JR, Ohashi PS, Penninger JM. Nishina H, et al. J Exp Med. 1997 Sep 15;186(6):941-53. doi: 10.1084/jem.186.6.941. J Exp Med. 1997. PMID: 9294148 Free PMC article.
The stress kinase mitogen-activated protein kinase kinase (MKK)7 is a negative regulator of antigen receptor and growth factor receptor-induced proliferation in hematopoietic cells.
Sasaki T, Wada T, Kishimoto H, Irie-Sasaki J, Matsumoto G, Goto T, Yao Z, Wakeham A, Mak TW, Suzuki A, Cho SK, Zuniga-Pflucker JC, Oliveira-dos-Santos AJ, Katada T, Nishina H, Penninger JM. Sasaki T, et al. Among authors: nishina h. J Exp Med. 2001 Sep 17;194(6):757-68. doi: 10.1084/jem.194.6.757. J Exp Med. 2001. PMID: 11560992 Free PMC article.
Impaired synergistic activation of stress-activated protein kinase SAPK/JNK in mouse embryonic stem cells lacking SEK1/MKK4: different contribution of SEK2/MKK7 isoforms to the synergistic activation.
Wada T, Nakagawa K, Watanabe T, Nishitai G, Seo J, Kishimoto H, Kitagawa D, Sasaki T, Penninger JM, Nishina H, Katada T. Wada T, et al. Among authors: nishina h. J Biol Chem. 2001 Aug 17;276(33):30892-7. doi: 10.1074/jbc.M011780200. Epub 2001 Jun 19. J Biol Chem. 2001. PMID: 11418587 Free article.
320 results