Heinrich PC - Search Results

1

Molecular modeling-guided mutagenesis of the extracellular part of gp130 leads to the identification of contact sites in the interleukin-6 (IL-6).IL-6 receptor.gp130 complex.

Horsten U, Müller-Newen G, Gerhartz C, Wollmer A, Wijdenes J, Heinrich PC, Grötzinger J. Horsten U, et al. Among authors: heinrich pc. J Biol Chem. 1997 Sep 19;272(38):23748-57. doi: 10.1074/jbc.272.38.23748. J Biol Chem. 1997. PMID: 9295319 Free article.

2

A fusion protein of the gp130 and interleukin-6Ralpha ligand-binding domains acts as a potent interleukin-6 inhibitor.

Ancey C, Küster A, Haan S, Herrmann A, Heinrich PC, Müller-Newen G. Ancey C, et al. Among authors: heinrich pc. J Biol Chem. 2003 May 9;278(19):16968-72. doi: 10.1074/jbc.C300081200. Epub 2003 Mar 19. J Biol Chem. 2003. PMID: 12646580 Free article.

3

Long term association of the cytokine receptor gp130 and the Janus kinase Jak1 revealed by FRAP analysis.

Giese B, Au-Yeung CK, Herrmann A, Diefenbach S, Haan C, Küster A, Wortmann SB, Roderburg C, Heinrich PC, Behrmann I, Müller-Newen G. Giese B, et al. Among authors: heinrich pc. J Biol Chem. 2003 Oct 3;278(40):39205-13. doi: 10.1074/jbc.M303347200. Epub 2003 Jul 23. J Biol Chem. 2003. PMID: 12878601 Free article.

4

Characterization of the Interleukin (IL)-6 Inhibitor IL-6-RFP: fused receptor domains act as high affinity cytokine-binding proteins.

Metz S, Wiesinger M, Vogt M, Lauks H, Schmalzing G, Heinrich PC, Müller-Newen G. Metz S, et al. Among authors: heinrich pc. J Biol Chem. 2007 Jan 12;282(2):1238-48. doi: 10.1074/jbc.M606885200. Epub 2006 Nov 3. J Biol Chem. 2007. PMID: 17085445 Free article.

5

Novel inhibitors for murine and human leukemia inhibitory factor based on fused soluble receptors.

Metz S, Naeth G, Heinrich PC, Müller-Newen G. Metz S, et al. Among authors: heinrich pc. J Biol Chem. 2008 Mar 7;283(10):5985-95. doi: 10.1074/jbc.M706610200. Epub 2008 Jan 3. J Biol Chem. 2008. PMID: 18174171 Free article.

6

The membrane distal half of gp130 is responsible for the formation of a ternary complex with IL-6 and the IL-6 receptor.

Horsten U, Schmitz-Van de Leur H, Müllberg J, Heinrich PC, Rose-John S. Horsten U, et al. Among authors: heinrich pc. FEBS Lett. 1995 Feb 20;360(1):43-6. doi: 10.1016/0014-5793(95)00053-c. FEBS Lett. 1995. PMID: 7875298 Free article.

7

Biosynthesis and half-life of the interleukin-6 receptor and its signal transducer gp130.

Gerhartz C, Dittrich E, Stoyan T, Rose-John S, Yasukawa K, Heinrich PC, Graeve L. Gerhartz C, et al. Among authors: heinrich pc. Eur J Biochem. 1994 Jul 1;223(1):265-74. doi: 10.1111/j.1432-1033.1994.tb18991.x. Eur J Biochem. 1994. PMID: 8033901 Free article.

8

Identification of a region within the cytoplasmic domain of the interleukin-6 (IL-6) signal transducer gp130 important for ligand-induced endocytosis of the IL-6 receptor.

Dittrich E, Rose-John S, Gerhartz C, Müllberg J, Stoyan T, Yasukawa K, Heinrich PC, Graeve L. Dittrich E, et al. Among authors: heinrich pc. J Biol Chem. 1994 Jul 22;269(29):19014-20. J Biol Chem. 1994. PMID: 8034658 Free article.

9

Use of immobilized synthetic peptides for the identification of contact sites between human interleukin-6 and its receptor.

Weiergräber O, Schneider-Mergener J, Grötzinger J, Wollmer A, Küster A, Exner M, Heinrich PC. Weiergräber O, et al. Among authors: heinrich pc. FEBS Lett. 1996 Jan 29;379(2):122-6. doi: 10.1016/0014-5793(95)01482-9. FEBS Lett. 1996. PMID: 8635575 Free article.

10

Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation.

Gerhartz C, Heesel B, Sasse J, Hemmann U, Landgraf C, Schneider-Mergener J, Horn F, Heinrich PC, Graeve L. Gerhartz C, et al. Among authors: heinrich pc. J Biol Chem. 1996 May 31;271(22):12991-8. doi: 10.1074/jbc.271.22.12991. J Biol Chem. 1996. PMID: 8662591 Free article.

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