Ojima I - Search Results

1

Anti-proliferative activity of a new class of taxanes (14beta-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells.

Distefano M, Scambia G, Ferlini C, Gaggini C, De Vincenzo R, Riva A, Bombardelli E, Ojima I, Fattorossi A, Panici PB, Mancuso S. Distefano M, et al. Among authors: ojima i. Int J Cancer. 1997 Sep 4;72(5):844-50. doi: 10.1002/(sici)1097-0215(19970904)72:5<844::aid-ijc22>3.0.co;2-7. Int J Cancer. 1997. PMID: 9311603

2

Second generation taxanes: from the natural framework to the challenge of drug resistance.

Ferlini C, Ojima I, Distefano M, Gallo D, Riva A, Morazzoni P, Bombardelli E, Mancuso S, Scambia G. Ferlini C, et al. Among authors: ojima i. Curr Med Chem Anticancer Agents. 2003 Mar;3(2):133-8. doi: 10.2174/1568011033353489. Curr Med Chem Anticancer Agents. 2003. PMID: 12678907 Review.

3

Antitumour activity of novel taxanes that act at the same time as cytotoxic agents and P-glycoprotein inhibitors.

Ferlini C, Distefano M, Pignatelli F, Lin S, Riva A, Bombardelli E, Mancuso S, Ojima I, Scambia G. Ferlini C, et al. Among authors: ojima i. Br J Cancer. 2000 Dec;83(12):1762-8. doi: 10.1054/bjoc.2000.1500. Br J Cancer. 2000. PMID: 11104578 Free PMC article.

4

Cytotoxic effects toward human hematopoietic progenitor cells and tumor cell lines of paclitaxel, docetaxel, and newly developed analogues IDN5109, IDN5111, and IDN5127.

Ferlini C, Distefano M, Pierelli L, Bonanno G, Riva A, Bombardelli E, Ojima I, Mancuso S, Scambia G. Ferlini C, et al. Among authors: ojima i. Oncol Res. 1999;11(10):471-8. Oncol Res. 1999. PMID: 10850888

5

New insights into drug resistance in cancer.

Ojima I, Ferlini C. Ojima I, et al. Chem Biol. 2003 Jul;10(7):583-4. doi: 10.1016/s1074-5521(03)00152-2. Chem Biol. 2003. PMID: 12890528 Free article.

6

Syntheses and biological activity of C-3'-difluoromethyl-taxoids.

Ojima I, Lin S, Slater JC, Wang T, Pera P, Bernacki RJ, Ferlini C, Scambia G. Ojima I, et al. Bioorg Med Chem. 2000 Jul;8(7):1619-28. doi: 10.1016/s0968-0896(00)00093-6. Bioorg Med Chem. 2000. PMID: 10976509

7

Effects of novel taxanes SB-T-1213 and IDN5109 on tubulin polymerization and mitosis.

Jordan MA, Ojima I, Rosas F, Distefano M, Wilson L, Scambia G, Ferlini C. Jordan MA, et al. Among authors: ojima i. Chem Biol. 2002 Jan;9(1):93-101. doi: 10.1016/s1074-5521(01)00097-7. Chem Biol. 2002. PMID: 11841942

8

Novel C-seco-taxoids possessing high potency against paclitaxel-resistant cancer cell lines overexpressing class III beta-tubulin.

Pepe A, Sun L, Zanardi I, Wu X, Ferlini C, Fontana G, Bombardelli E, Ojima I. Pepe A, et al. Among authors: ojima i. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3300-4. doi: 10.1016/j.bmcl.2009.04.070. Epub 2009 Apr 22. Bioorg Med Chem Lett. 2009. PMID: 19423340 Free PMC article.

9

Effects of orally active taxanes on P-glycoprotein modulation and colon and breast carcinoma drug resistance.

Vredenburg MR, Ojima I, Veith J, Pera P, Kee K, Cabral F, Sharma A, Kanter P, Greco WR, Bernacki RJ. Vredenburg MR, et al. Among authors: ojima i. J Natl Cancer Inst. 2001 Aug 15;93(16):1234-45. doi: 10.1093/jnci/93.16.1234. J Natl Cancer Inst. 2001. PMID: 11504769

10

New taxanes as highly efficient reversal agents for multidrug resistance in cancer cells.

Ojima I, Bounaud PY, Takeuchi C, Pera P, Bernacki RJ. Ojima I, et al. Bioorg Med Chem Lett. 1998 Jan 20;8(2):189-94. doi: 10.1016/s0960-894x(97)10218-9. Bioorg Med Chem Lett. 1998. PMID: 9871652

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