Luchman HA - Search Results

1

cDNA cloning of a novel, developmentally regulated immediate early gene activated by fibroblast growth factor and encoding a nuclear protein.

Paterno GD, Li Y, Luchman HA, Ryan PJ, Gillespie LL. Paterno GD, et al. Among authors: luchman ha. J Biol Chem. 1997 Oct 10;272(41):25591-5. doi: 10.1074/jbc.272.41.25591. J Biol Chem. 1997. PMID: 9325278 Free article.

2

Developmentally regulated cytoplasmic retention of the transcription factor XMI-ER1 requires sequence in the acidic activation domain.

Post JN, Luchman HA, Mercer FC, Paterno GD, Gillespie LL. Post JN, et al. Among authors: luchman ha. Int J Biochem Cell Biol. 2005 Feb;37(2):463-77. doi: 10.1016/j.biocel.2004.07.016. Int J Biochem Cell Biol. 2005. PMID: 15474990

3

Differential nuclear localization of ER1 protein during embryonic development in Xenopus laevis.

Luchman HA, Paterno GD, Kao KR, Gillespie LL. Luchman HA, et al. Mech Dev. 1999 Jan;80(1):111-4. doi: 10.1016/s0925-4773(98)00206-8. Mech Dev. 1999. PMID: 10096069 Free article.

4

Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer.

Shouksmith AE, Shah F, Grimard ML, Gawel JM, Raouf YS, Geletu M, Berger-Becvar A, de Araujo ED, Luchman HA, Heaton WL, Bakhshinyan D, Adile AA, Venugopal C, O'Hare T, Deininger MW, Singh SK, Konieczny SF, Weiss S, Fishel ML, Gunning PT. Shouksmith AE, et al. Among authors: luchman ha. J Med Chem. 2019 Mar 14;62(5):2651-2665. doi: 10.1021/acs.jmedchem.8b01957. Epub 2019 Mar 6. J Med Chem. 2019. PMID: 30776234 Free PMC article.

5

The JAK2/STAT3 inhibitor pacritinib effectively inhibits patient-derived GBM brain tumor initiating cells in vitro and when used in combination with temozolomide increases survival in an orthotopic xenograft model.

Jensen KV, Cseh O, Aman A, Weiss S, Luchman HA. Jensen KV, et al. Among authors: luchman ha. PLoS One. 2017 Dec 18;12(12):e0189670. doi: 10.1371/journal.pone.0189670. eCollection 2017. PLoS One. 2017. PMID: 29253028 Free PMC article.

6

Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma.

Haftchenary S, Luchman HA, Jouk AO, Veloso AJ, Page BD, Cheng XR, Dawson SS, Grinshtein N, Shahani VM, Kerman K, Kaplan DR, Griffin C, Aman AM, Al-Awar R, Weiss S, Gunning PT. Haftchenary S, et al. Among authors: luchman ha. ACS Med Chem Lett. 2013 Sep 8;4(11):1102-7. doi: 10.1021/ml4003138. eCollection 2013 Nov 14. ACS Med Chem Lett. 2013. PMID: 24900612 Free PMC article.

7

Dual mTORC1/2 blockade inhibits glioblastoma brain tumor initiating cells in vitro and in vivo and synergizes with temozolomide to increase orthotopic xenograft survival.

Luchman HA, Stechishin OD, Nguyen SA, Lun XQ, Cairncross JG, Weiss S. Luchman HA, et al. Clin Cancer Res. 2014 Nov 15;20(22):5756-67. doi: 10.1158/1078-0432.CCR-13-3389. Epub 2014 Oct 14. Clin Cancer Res. 2014. PMID: 25316808

8

On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells.

Stechishin OD, Luchman HA, Ruan Y, Blough MD, Nguyen SA, Kelly JJ, Cairncross JG, Weiss S. Stechishin OD, et al. Among authors: luchman ha. Neuro Oncol. 2013 Feb;15(2):198-207. doi: 10.1093/neuonc/nos302. Epub 2012 Dec 21. Neuro Oncol. 2013. PMID: 23262510 Free PMC article.

9

An in vivo patient-derived model of endogenous IDH1-mutant glioma.

Luchman HA, Stechishin OD, Dang NH, Blough MD, Chesnelong C, Kelly JJ, Nguyen SA, Chan JA, Weljie AM, Cairncross JG, Weiss S. Luchman HA, et al. Neuro Oncol. 2012 Feb;14(2):184-91. doi: 10.1093/neuonc/nor207. Epub 2011 Dec 13. Neuro Oncol. 2012. PMID: 22166263 Free PMC article.

10

Live-Cell Imaging Assays to Study Glioblastoma Brain Tumor Stem Cell Migration and Invasion.

Restall I, Bozek DA, Chesnelong C, Weiss S, Luchman HA. Restall I, et al. Among authors: luchman ha. J Vis Exp. 2018 Aug 29;(138):58152. doi: 10.3791/58152. J Vis Exp. 2018. PMID: 30222149 Free PMC article.

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