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Aspartate 171 is the major primate-specific determinant of human growth hormone. Engineering porcine growth hormone to activate the human receptor.
J Biol Chem. 1997 Oct 24;272(43):27077-83. doi: 10.1074/jbc.272.43.27077.
J Biol Chem. 1997.
PMID: 9341147
Free article.
Model for growth hormone receptor activation based on subunit rotation within a receptor dimer.
Brown RJ, Adams JJ, Pelekanos RA, Wan Y, McKinstry WJ, Palethorpe K, Seeber RM, Monks TA, Eidne KA, Parker MW, Waters MJ.
Brown RJ, et al. Among authors: monks ta.
Nat Struct Mol Biol. 2005 Sep;12(9):814-21. doi: 10.1038/nsmb977. Epub 2005 Aug 21.
Nat Struct Mol Biol. 2005.
PMID: 16116438
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Conopeptide ρ-TIA defines a new allosteric site on the extracellular surface of the α1B-adrenoceptor.
Ragnarsson L, Wang CI, Andersson Å, Fajarningsih D, Monks T, Brust A, Rosengren KJ, Lewis RJ.
Ragnarsson L, et al.
J Biol Chem. 2013 Jan 18;288(3):1814-27. doi: 10.1074/jbc.M112.430785. Epub 2012 Nov 26.
J Biol Chem. 2013.
PMID: 23184947
Free PMC article.
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