Danhof M - Search Results

1

Mechanism-based pharmacokinetic-pharmacodynamic modeling of the effects of N6-cyclopentyladenosine analogs on heart rate in rat: estimation of in vivo operational affinity and efficacy at adenosine A1 receptors.

Van Der Graaf PH, Van Schaick EA, Math-ot RA, Ijzerman AP, Danhof M. Van Der Graaf PH, et al. Among authors: danhof m. J Pharmacol Exp Ther. 1997 Nov;283(2):809-16. J Pharmacol Exp Ther. 1997. PMID: 9353402

2

A competitive interaction model predicts the effect of WAY-100,635 on the time course of R-(+)-8-hydroxy-2-(di-n-propylamino)tetralin-induced hypothermia.

Zuideveld KP, Treijtel N, Maas HJ, Gubbens-Stibbe JM, Peletier LA, van Der Graaf PH, Danhof M. Zuideveld KP, et al. Among authors: danhof m. J Pharmacol Exp Ther. 2002 Jan;300(1):330-8. doi: 10.1124/jpet.300.1.330. J Pharmacol Exp Ther. 2002. PMID: 11752133

3

Pharmacokinetic-pharmacodynamic modeling of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine in rats.

Zuideveld KP, Rusiç-Pavletiç J, Maas HJ, Peletier LA, Van der Graaf PH, Danhof M. Zuideveld KP, et al. Among authors: danhof m. J Pharmacol Exp Ther. 2002 Dec;303(3):1130-7. doi: 10.1124/jpet.102.036798. J Pharmacol Exp Ther. 2002. PMID: 12438536

4

Adenosine A1 receptor agonist N6-cyclopentyladenosine affects the inactivation of acetylcholinesterase in blood and brain by sarin.

Bueters TJ, Joosen MJ, van Helden HP, Ijzerman AP, Danhof M. Bueters TJ, et al. Among authors: danhof m. J Pharmacol Exp Ther. 2003 Mar;304(3):1307-13. doi: 10.1124/jpet.102.044644. J Pharmacol Exp Ther. 2003. PMID: 12604711

5

Mechanism-based pharmacokinetic-pharmacodynamic modeling of 5-HT1A receptor agonists: estimation of in vivo affinity and intrinsic efficacy on body temperature in rats.

Zuideveld KP, Van der Graaf PH, Newgreen D, Thurlow R, Petty N, Jordan P, Peletier LA, Danhof M. Zuideveld KP, et al. Among authors: danhof m. J Pharmacol Exp Ther. 2004 Mar;308(3):1012-20. doi: 10.1124/jpet.103.059030. Epub 2004 Jan 8. J Pharmacol Exp Ther. 2004. PMID: 14718609

6

Population pharmacokinetic-pharmacodynamic modelling of the anti-hyperalgesic effect of 5'deoxy-N6-cylopentyladenosine in the mononeuropathic rat.

Schaddelee MP, Dejongh J, Collins SD, de Boer AG, Ijzerman AP, Danhof M. Schaddelee MP, et al. Among authors: danhof m. Eur J Pharmacol. 2004 Nov 3;504(1-2):7-15. doi: 10.1016/j.ejphar.2004.09.029. Eur J Pharmacol. 2004. PMID: 15507215

7

Towards a mechanism-based analysis of pharmacodynamic drug-drug interactions in vivo.

Jonker DM, Visser SA, van der Graaf PH, Voskuyl RA, Danhof M. Jonker DM, et al. Among authors: danhof m. Pharmacol Ther. 2005 Apr;106(1):1-18. doi: 10.1016/j.pharmthera.2004.10.014. Epub 2004 Dec 23. Pharmacol Ther. 2005. PMID: 15781119 Review.

8

Pharmacokinetic/pharmacodynamic modelling of the anti-hyperalgesic and anti-nociceptive effect of adenosine A1 receptor partial agonists in neuropathic pain.

Schaddelee MP, Collins SD, DeJongh J, de Boer AG, Ijzerman AP, Danhof M. Schaddelee MP, et al. Among authors: danhof m. Eur J Pharmacol. 2005 May 9;514(2-3):131-40. doi: 10.1016/j.ejphar.2005.03.026. Eur J Pharmacol. 2005. PMID: 15910799

9

Quantification of the in vivo potency of the adenosine A2 receptor antagonist 8-(3-chlorostyryl)caffeine.

Mathôt RA, Gubbens-Stibbe JM, Soudijn W, Jacobson KA, Ijzerman AP, Danhof M. Mathôt RA, et al. Among authors: danhof m. J Pharmacol Exp Ther. 1995 Oct;275(1):245-53. J Pharmacol Exp Ther. 1995. PMID: 7562557 Free PMC article.

10

Ribose-modified adenosine analogues as potential partial agonists for the adenosine receptor.

van der Wenden EM, von Frijtag Drabbe Künzel JK, Mathôt RA, Danhof M, IJzerman AP, Soudijn W. van der Wenden EM, et al. Among authors: danhof m. J Med Chem. 1995 Sep 29;38(20):4000-6. doi: 10.1021/jm00020a014. J Med Chem. 1995. PMID: 7562934

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