Frye RF - Search Results

1

Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolizing enzymes.

Frye RF, Matzke GR, Adedoyin A, Porter JA, Branch RA. Frye RF, et al. Clin Pharmacol Ther. 1997 Oct;62(4):365-76. doi: 10.1016/S0009-9236(97)90114-4. Clin Pharmacol Ther. 1997. PMID: 9357387 Clinical Trial.

2

Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N-acetyltransferase in healthy human subjects.

Frye RF, Branch RA. Frye RF, et al. Br J Clin Pharmacol. 2002 Feb;53(2):155-62. doi: 10.1046/j.1365-2125.2002.01522.x. Br J Clin Pharmacol. 2002. PMID: 11851639 Free PMC article.

3

Coordinated intrahepatic and extrahepatic regulation of cytochrome p4502D6 in healthy subjects and in patients after liver transplantation.

Carcillo JA, Adedoyin A, Burckart GJ, Frye RF, Venkataramanan R, Knoll C, Thummel K, Roskos L, Wilson JW, Sereika S, Romkes M, Bebia Z, Branch RA. Carcillo JA, et al. Among authors: frye rf. Clin Pharmacol Ther. 2003 May;73(5):456-67. doi: 10.1016/s0009-9236(03)00055-9. Clin Pharmacol Ther. 2003. PMID: 12732845 Clinical Trial.

4

Impaired 6-hydroxychlorzoxazone elimination in patients with kidney disease: Implication for cytochrome P450 2E1 pharmacogenetic studies.

Nolin TD, Gastonguay MR, Bies RR, Matzke GR, Frye RF. Nolin TD, et al. Among authors: frye rf. Clin Pharmacol Ther. 2003 Dec;74(6):555-68. doi: 10.1016/j.clpt.2003.09.003. Clin Pharmacol Ther. 2003. PMID: 14663458 Clinical Trial.

5

Bioequivalence revisited: influence of age and sex on CYP enzymes.

Bebia Z, Buch SC, Wilson JW, Frye RF, Romkes M, Cecchetti A, Chaves-Gnecco D, Branch RA. Bebia Z, et al. Among authors: frye rf. Clin Pharmacol Ther. 2004 Dec;76(6):618-27. doi: 10.1016/j.clpt.2004.08.021. Clin Pharmacol Ther. 2004. PMID: 15592333

6

Liver disease selectively modulates cytochrome P450--mediated metabolism.

Frye RF, Zgheib NK, Matzke GR, Chaves-Gnecco D, Rabinovitz M, Shaikh OS, Branch RA. Frye RF, et al. Clin Pharmacol Ther. 2006 Sep;80(3):235-45. doi: 10.1016/j.clpt.2006.05.006. Clin Pharmacol Ther. 2006. PMID: 16952490 Clinical Trial.

7

Validation of incorporating flurbiprofen into the Pittsburgh cocktail.

Zgheib NK, Frye RF, Tracy TS, Romkes M, Branch RA. Zgheib NK, et al. Among authors: frye rf. Clin Pharmacol Ther. 2006 Sep;80(3):257-63. doi: 10.1016/j.clpt.2006.06.005. Clin Pharmacol Ther. 2006. PMID: 16952492 Clinical Trial.

8

Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6-hydroxylation.

Burckart GJ, Frye RF, Kelly P, Branch RA, Jain A, Fung JJ, Starzl TE, Venkataramanan R. Burckart GJ, et al. Among authors: frye rf. Clin Pharmacol Ther. 1998 Mar;63(3):296-302. doi: 10.1016/S0009-9236(98)90161-8. Clin Pharmacol Ther. 1998. PMID: 9542473 Free PMC article.

9

Use of chlorzoxazone as an in vivo probe of cytochrome P450 2E1: choice of dose and phenotypic trait measure.

Frye RF, Adedoyin A, Mauro K, Matzke GR, Branch RA. Frye RF, et al. J Clin Pharmacol. 1998 Jan;38(1):82-9. doi: 10.1002/j.1552-4604.1998.tb04381.x. J Clin Pharmacol. 1998. PMID: 9597564

10

Chloroquine modulation of specific metabolizing enzymes activities: investigation with selective five drug cocktail.

Adedoyin A, Frye RF, Mauro K, Branch RA. Adedoyin A, et al. Among authors: frye rf. Br J Clin Pharmacol. 1998 Sep;46(3):215-9. doi: 10.1046/j.1365-2125.1998.00765.x. Br J Clin Pharmacol. 1998. PMID: 9764961 Free PMC article.

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